2d-hplc-ms-technology-combined-with-molecular-network-for

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine <i>Aconitum pendulum  </i>

In this study, a comprehensive approach was employed, utilizing 2D-HPLC-MS technology in conjunction with the molecular network to unravel the intricate ...

Chengdu University of Traditional Chinese Medicine

 D. Don is the major source plants of traditional Chinese medicine Fritillariae Cirrhosae Bulbus (FCB). Domestication, introduction, and cultivation is an important strategy to alleviate the shortage of endangered medicinal plants of . However, until now, the yield and quality changes of FCB in different harvest periods and drying treatments after harvest were not well understood. Therefore, in this paper, we investigated the yield and quality of cultivated  at different harvest periods and postharvest processing methods. The results showed that dry weight per bulb ranged from 0.8913 to 1.4681 g and reached the highest at the wilting stage. The soluble sugar content ranged from 0.075% to 0.127% and reached the highest at the wilting stage. The content of total alkaloids ranged from 0.088% to 0.218% and reached the highest at the late-flowering stage. The contents of peimisine, sipeimine, peimine, and peiminine were 0.01178%-0.02615%, 0%-0.01713%, 0%-0.00745%, and 0%-0.00621% and reached the highest at the late-flowering period, wilting period, young fruit period, and initial flowering period, respectively. For the two different postharvest processing methods, the contents of total alkaloids and the 16 main characteristic peaks did not exhibit significant differences. Still, the alkaloid contents of the oven drying after washing were slightly higher than the sun drying. In conclusion, the best harvest period is the wilting period of , and oven drying after washing is more beneficial to ensure the quality of FCB and improve productivity.

Jing Ma

Ethnic Medicine Academic Heritage Innovation Research Center,
Meishan Hospital,
Ethnic Medicine Academic Heritage Innovation Research Center, Meishan Hospital

Chengdu University of Traditional Chinese Medicine

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum

Jing Ma

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Chengdu University of Traditional Chinese Medicine

2D-HPLC-MS Technology Combined with Molecular Network for the Identification of Components in Tibetan Medicine Aconitum pendulum

Ethnic Medicine Academic Heritage Innovation Research Center,
Meishan Hospital,
Ethnic Medicine Academic Heritage Innovation Research Center, Meishan Hospital