Centre of Perinatal Medicine and Health,
Institute of Neuroscience and Physiology,
Sahlgrenska Academy,
Centre of Perinatal Medicine and Health, Institute of Neuroscience and Physiology, Sahlgrenska Academy
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Single-cell atlas reveals meningeal leukocyte heterogeneity in the developing mouse brain.
Genes & development Aug, 2021 | Pubmed ID: 34301765
Function and Biomarkers of the Blood-Brain Barrier in a Neonatal Germinal Matrix Haemorrhage Model.
Cells Jul, 2021 | Pubmed ID: 34359845
ECG and heart rate variability changes in preterm and near-term fetal lamb following LPS exposure.
Reproductive sciences (Thousand Oaks, Calif.) Jul, 2008 | Pubmed ID: 18456675
Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2009 | Pubmed ID: 19244535
White matter damage after chronic subclinical inflammation in newborn mice.
Journal of child neurology Sep, 2009 | Pubmed ID: 19745089
Lipopolysaccharide sensitizes neonatal hypoxic-ischemic brain injury in a MyD88-dependent manner.
Journal of immunology (Baltimore, Md. : 1950) Dec, 2009 | Pubmed ID: 19917690
The role of Toll-like receptors in perinatal brain injury.
Clinics in perinatology Dec, 2009 | Pubmed ID: 19944834
Galectin-3 contributes to neonatal hypoxic-ischemic brain injury.
Neurobiology of disease Apr, 2010 | Pubmed ID: 20053377
Attenuation of reactive gliosis does not affect infarct volume in neonatal hypoxic-ischemic brain injury in mice.
PloS one Apr, 2010 | Pubmed ID: 20442854
Neuroprotective effect of Bax-inhibiting peptide on neonatal brain injury.
Stroke; a journal of cerebral circulation Sep, 2010 | Pubmed ID: 20671246
The Nrf2-inducible antioxidant defense in astrocytes can be both up- and down-regulated by activated microglia:Involvement of p38 MAPK.
Glia May, 2011 | Pubmed ID: 21351160
Learning and activity after irradiation of the young mouse brain analyzed in adulthood using unbiased monitoring in a home cage environment.
Radiation research Mar, 2011 | Pubmed ID: 21388277
Regulation of toll-like receptor 1 and -2 in neonatal mice brains after hypoxia-ischemia.
Journal of neuroinflammation May, 2011 | Pubmed ID: 21569241
Systemic stimulation of TLR2 impairs neonatal mouse brain development.
PloS one May, 2011 | Pubmed ID: 21573120
Safety aspects of longitudinal administration of IGF-I/IGFBP-3 complex in neonatal mice.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society Aug, 2011 | Pubmed ID: 21696987
Activated microglia decrease histone acetylation and Nrf2-inducible anti-oxidant defence in astrocytes: restoring effects of inhibitors of HDACs, p38 MAPK and GSK3β.
Neurobiology of disease Oct, 2011 | Pubmed ID: 21757005
Trace fear conditioning detects hypoxic-ischemic brain injury in neonatal mice.
Developmental neuroscience , 2011 | Pubmed ID: 21778703
Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep.
Annals of neurology Nov, 2011 | Pubmed ID: 22002627
Infection-induced vulnerability of perinatal brain injury.
Neurology research international , 2012 | Pubmed ID: 22135745
Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury.
PloS one , 2011 | Pubmed ID: 22242129
Combined effect of hypothermia and caspase-2 gene deficiency on neonatal hypoxic-ischemic brain injury.
Pediatric research May, 2012 | Pubmed ID: 22322383
Which neuroprotective agents are ready for bench to bedside translation in the newborn infant?
The Journal of pediatrics Apr, 2012 | Pubmed ID: 22325255
Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury.
Journal of neuroinflammation Apr, 2012 | Pubmed ID: 22512781
From mice to women and back again: causalities and clues for Chlamydia-induced tubal ectopic pregnancy.
Fertility and sterility Nov, 2012 | Pubmed ID: 22884019
Dual TNFα-induced effects on NRF2 mediated antioxidant defence in astrocyte-rich cultures: role of protein kinase activation.
Neurochemical research Dec, 2012 | Pubmed ID: 22941452
Pathological changes in the white matter after spinal contusion injury in the rat.
PloS one , 2012 | Pubmed ID: 22952690
A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses.
PloS one , 2012 | Pubmed ID: 22970147
Innate immune regulation by toll-like receptors in the brain.
ISRN neurology , 2012 | Pubmed ID: 23097717
Expression of the Nrf2-system at the blood-CSF barrier is modulated by neonatal inflammation and hypoxia-ischemia.
Journal of inherited metabolic disease May, 2013 | Pubmed ID: 23109062
Interaction of inflammation and hyperoxia in a rat model of neonatal white matter damage.
PloS one , 2012 | Pubmed ID: 23155446
Radixin expression in microglia after cortical stroke lesion.
Glia May, 2013 | Pubmed ID: 23440885
Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro.
Brain, behavior, and immunity Aug, 2013 | Pubmed ID: 23454862
Time-dependent effects of systemic lipopolysaccharide injection on regulators of antioxidant defence Nrf2 and PGC-1α in the neonatal rat brain.
Neuroimmunomodulation , 2013 | Pubmed ID: 23635713
Receptor for complement peptide C3a: a therapeutic target for neonatal hypoxic-ischemic brain injury.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2013 | Pubmed ID: 23737250
Regulation of Toll-like receptors in the choroid plexus in the immature brain after systemic inflammatory stimuli.
Translational stroke research Apr, 2013 | Pubmed ID: 23741282
Preface.
Developmental neuroscience , 2013 | Pubmed ID: 23796853
Toll-like receptor-3 activation increases the vulnerability of the neonatal brain to hypoxia-ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2013 | Pubmed ID: 23864690
Death associated protein kinases: molecular structure and brain injury.
International journal of molecular sciences , 2013 | Pubmed ID: 23880846
NRF2-regulation in brain health and disease: implication of cerebral inflammation.
Neuropharmacology Apr, 2014 | Pubmed ID: 24262633
Astrocytes and microglia in acute cerebral injury underlying cerebral palsy associated with preterm birth.
Pediatric research Jan, 2014 | Pubmed ID: 24336433
Innate defense regulator peptide 1018 protects against perinatal brain injury.
Annals of neurology Mar, 2014 | Pubmed ID: 24339166
Perinatal hypoxia-ischemia reduces α 7 nicotinic receptor expression and selective α 7 nicotinic receptor stimulation suppresses inflammation and promotes microglial Mox phenotype.
BioMed research international , 2014 | Pubmed ID: 24757672
Microglia toxicity in preterm brain injury.
Reproductive toxicology (Elmsford, N.Y.) Sep, 2014 | Pubmed ID: 24768662
Infection-induced inflammation and cerebral injury in preterm infants.
The Lancet. Infectious diseases Aug, 2014 | Pubmed ID: 24877996
Exendin-4 reduces ischemic brain injury in normal and aged type 2 diabetic mice and promotes microglial M2 polarization.
PloS one , 2014 | Pubmed ID: 25101679
The immune response after hypoxia-ischemia in a mouse model of preterm brain injury.
Journal of neuroinflammation Sep, 2014 | Pubmed ID: 25187205
The effect of osteopontin and osteopontin-derived peptides on preterm brain injury.
Journal of neuroinflammation Dec, 2014 | Pubmed ID: 25465048
Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism May, 2015 | Pubmed ID: 25627141
The role of inflammation in perinatal brain injury.
Nature reviews. Neurology Apr, 2015 | Pubmed ID: 25686754
Potential neuroprotective strategies for perinatal infection and inflammation.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience Oct, 2015 | Pubmed ID: 25702527
Transcriptomal changes and functional annotation of the developing non-human primate choroid plexus.
Frontiers in neuroscience , 2015 | Pubmed ID: 25814924
Does Caspase-6 Have a Role in Perinatal Brain Injury?
Developmental neuroscience , 2015 | Pubmed ID: 25823427
Staphylococcus epidermidis Bacteremia Induces Brain Injury in Neonatal Mice via Toll-like Receptor 2-Dependent and -Independent Pathways.
The Journal of infectious diseases Nov, 2015 | Pubmed ID: 25883383
Expression of tight junction proteins and transporters for xenobiotic metabolism at the blood-CSF barrier during development in the nonhuman primate (P. hamadryas).
Reproductive toxicology (Elmsford, N.Y.) Aug, 2015 | Pubmed ID: 26092209
Modeling Ischemia in the Immature Brain: How Translational Are Animal Models?
Stroke Oct, 2015 | Pubmed ID: 26272384
GSK3β inhibition protects the immature brain from hypoxic-ischaemic insult via reduced STAT3 signalling.
Neuropharmacology Feb, 2016 | Pubmed ID: 26384655
New means to assess neonatal inflammatory brain injury.
Journal of neuroinflammation Sep, 2015 | Pubmed ID: 26407958
The consequences of fetal growth restriction on brain structure and neurodevelopmental outcome.
The Journal of physiology Feb, 2016 | Pubmed ID: 26607046
Editorial: White blood cells matter in neonatal white-matter injury.
Journal of leukocyte biology Jan, 2016 | Pubmed ID: 26733001
Cerebrospinal fluid levels of insulin, leptin, and agouti-related protein in relation to BMI in pregnant women.
Obesity (Silver Spring, Md.) Jun, 2016 | Pubmed ID: 27130070
TLR2-mediated leukocyte trafficking to the developing brain.
Journal of leukocyte biology Jan, 2017 | Pubmed ID: 27493242
Spirulina diet to lactating mothers protects the antioxidant system and reduces inflammation in post-natal brain after systemic inflammation.
Nutritional neuroscience Jan, 2018 | Pubmed ID: 27571388
Neonatal microglia: The cornerstone of brain fate.
Brain, behavior, and immunity Jan, 2017 | Pubmed ID: 27596692
Diabetes negatively affects cortical and striatal GABAergic neurons: an effect that is partially counteracted by exendin-4.
Bioscience reports Dec, 2016 | Pubmed ID: 27780892
Immune responses in perinatal brain injury.
Brain, behavior, and immunity Jul, 2017 | Pubmed ID: 27865947
Sustained Effects of Neonatal Systemic Lipopolysaccharide on IL-1β and Nrf2 in Adult Rat Substantia Nigra Are Partly Normalized by a Spirulina-Enriched Diet.
Neuroimmunomodulation , 2016 | Pubmed ID: 27931028
Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury.
Frontiers in cellular neuroscience , 2016 | Pubmed ID: 28018179
Intranasal C3a treatment ameliorates cognitive impairment in a mouse model of neonatal hypoxic-ischemic brain injury.
Experimental neurology Apr, 2017 | Pubmed ID: 28062175
Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia.
Oncotarget Feb, 2017 | Pubmed ID: 28076846
Systemic activation of Toll-like receptor 2 suppresses mitochondrial respiration and exacerbates hypoxic-ischemic injury in the developing brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Apr, 2017 | Pubmed ID: 28139935
Elevated levels of circulating cell-free DNA and neutrophil proteins are associated with neonatal sepsis and necrotizing enterocolitis in immature mice, pigs and infants.
Innate immunity Aug, 2017 | Pubmed ID: 28714327
Effect of Neuroinflammation on Synaptic Organization and Function in the Developing Brain: Implications for Neurodevelopmental and Neurodegenerative Disorders.
Frontiers in cellular neuroscience , 2017 | Pubmed ID: 28744200
Mitochondria, Bioenergetics and Excitotoxicity: New Therapeutic Targets in Perinatal Brain Injury.
Frontiers in cellular neuroscience , 2017 | Pubmed ID: 28747873
Translational Stroke Research: Vision and Opportunities.
Stroke Sep, 2017 | Pubmed ID: 28751554
Cell Death in the Developing Brain after Hypoxia-Ischemia.
Frontiers in cellular neuroscience , 2017 | Pubmed ID: 28878624
Central and Peripheral Leptin and Agouti-Related Protein during and after Pregnancy in Relation to Weight Change.
Clinical endocrinology Nov, 2017 | Pubmed ID: 29154467
γδ T Cells Contribute to Injury in the Developing Brain.
The American journal of pathology Mar, 2018 | Pubmed ID: 29248460
γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in mice.
Journal of neuroinflammation Dec, 2017 | Pubmed ID: 29262837
Mitochondrial dynamics, mitophagy and biogenesis in neonatal hypoxic-ischaemic brain injury.
FEBS letters Mar, 2018 | Pubmed ID: 29265370
Microglia and Neonatal Brain Injury.
Neuroscience 05, 2019 | Pubmed ID: 29352997
The myth of the immature barrier systems in the developing brain: role in perinatal brain injury.
The Journal of physiology Dec, 2018 | Pubmed ID: 29528501
Lymphocytes Contribute to the Pathophysiology of Neonatal Brain Injury.
Frontiers in neurology , 2018 | Pubmed ID: 29615958
Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury.
Brain, behavior, and immunity Nov, 2018 | Pubmed ID: 30218783
Peripheral myeloid cells contribute to brain injury in male neonatal mice.
Journal of neuroinflammation Oct, 2018 | Pubmed ID: 30376851
Lack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal hypoxia-ischemia.
Cell death & disease Dec, 2018 | Pubmed ID: 30584234
A novel image segmentation method for the evaluation of inflammation-induced cortical and hippocampal white matter injury in neonatal mice.
Journal of chemical neuroanatomy Mar, 2019 | Pubmed ID: 30586607
Lipopolysaccharide-induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo.
Glia Jun, 2019 | Pubmed ID: 30637805
Bestrophin-3 Expression in a Subpopulation of Astrocytes in the Neonatal Brain After Hypoxic-Ischemic Injury.
Frontiers in physiology , 2019 | Pubmed ID: 30761013
Choroid plexus transcriptome and ultrastructure analysis reveals a TLR2-specific chemotaxis signature and cytoskeleton remodeling in leukocyte trafficking.
Brain, behavior, and immunity Jul, 2019 | Pubmed ID: 30822467
The Role of Mitochondrial and Endoplasmic Reticulum Reactive Oxygen Species Production in Models of Perinatal Brain Injury.
Antioxidants & redox signaling Sep, 2019 | Pubmed ID: 30957515
Genetic or Other Causation Should Not Change the Clinical Diagnosis of Cerebral Palsy.
Journal of child neurology Jul, 2019 | Pubmed ID: 30963790
Evidence for Sexual Dimorphism in the Response to TLR3 Activation in the Developing Neonatal Mouse Brain: A Pilot Study.
Frontiers in physiology , 2019 | Pubmed ID: 30971945
Sex-Dependent Effects of Perinatal Inflammation on the Brain: Implication for Neuro-Psychiatric Disorders.
International journal of molecular sciences May, 2019 | Pubmed ID: 31071949
Dysmaturation of Somatostatin Interneurons Following Umbilical Cord Occlusion in Preterm Fetal Sheep.
Frontiers in physiology , 2019 | Pubmed ID: 31178744
Positive and negative conditioning in the neonatal brain.
Conditioning medicine Oct, 2018 | Pubmed ID: 31214666
Longitudinal changes in adipokines and free leptin index during and after pregnancy in women with obesity.
International journal of obesity (2005) Mar, 2020 | Pubmed ID: 31551485
Microbial invasion of the amniotic cavity is associated with impaired cognitive and motor function at school age in preterm children.
Pediatric research Apr, 2020 | Pubmed ID: 31711067
Vancomycin Is Protective in a Neonatal Mouse Model of -Potentiated Hypoxic-Ischemic Brain Injury.
Antimicrobial agents and chemotherapy Feb, 2020 | Pubmed ID: 31818825
N-acetylcysteine inhibits bacterial lipopeptide-mediated neutrophil transmigration through the choroid plexus in the developing brain.
Acta neuropathologica communications Jan, 2020 | Pubmed ID: 31973769
Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice.
Cell death & disease Jan, 2020 | Pubmed ID: 32001673
Flinders sensitive line rats are resistant to infarction following transient occlusion of the middle cerebral artery.
Brain research Jun, 2020 | Pubmed ID: 32194078
Inhibiting the interaction between apoptosis-inducing factor and cyclophilin A prevents brain injury in neonatal mice after hypoxia-ischemia.
Neuropharmacology Jul, 2020 | Pubmed ID: 32277944
Sensitizes Perinatal Hypoxic-Ischemic Brain Injury in Male but Not Female Mice.
Frontiers in immunology , 2020 | Pubmed ID: 32373108
A Systematic Review of Magnesium Sulfate for Perinatal Neuroprotection: What Have We Learnt From the Past Decade?
Frontiers in neurology , 2020 | Pubmed ID: 32536903
Expression of S100A Alarmins in Cord Blood Monocytes Is Highly Associated With Chorioamnionitis and Fetal Inflammation in Preterm Infants.
Frontiers in immunology , 2020 | Pubmed ID: 32612607
Type 2 Innate Lymphoid Cells Accumulate in the Brain After Hypoxia-Ischemia but Do Not Contribute to the Development of Preterm Brain Injury.
Frontiers in cellular neuroscience , 2020 | Pubmed ID: 32848629
Infant body composition relationship to maternal adipokines and fat mass: the PONCH study.
Pediatric research May, 2021 | Pubmed ID: 32927470
Association between inflammatory response and outcome after subarachnoid haemorrhage.
Acta neurologica Scandinavica Feb, 2021 | Pubmed ID: 32990943
Neuroprotection offered by mesenchymal stem cells in perinatal brain injury: Role of mitochondria, inflammation, and reactive oxygen species.
Journal of neurochemistry 07, 2021 | Pubmed ID: 33314066
Dual Profile of Environmental Enrichment and Autistic-Like Behaviors in the Maternal Separated Model in Rats.
International journal of molecular sciences Jan, 2021 | Pubmed ID: 33503967
Growth-differentiation-factor 15 levels in obese and healthy pregnancies: Relation to insulin resistance and insulin secretory function.
Clinical endocrinology Jul, 2021 | Pubmed ID: 33547817
Circulating tight-junction proteins are potential biomarkers for blood-brain barrier function in a model of neonatal hypoxic/ischemic brain injury.
Fluids and barriers of the CNS Feb, 2021 | Pubmed ID: 33568200
The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia-reperfusion brain injury in mice.
Bioscience reports Jun, 2021 | Pubmed ID: 34008839
Growth differentiation factor 15 increases in both cerebrospinal fluid and serum during pregnancy.
PloS one , 2021 | Pubmed ID: 34043633
Galectin-3 Modulates Microglia Inflammation in vitro but Not Neonatal Brain Injury in vivo under Inflammatory Conditions.
Developmental neuroscience , 2021 | Pubmed ID: 34130282
Viral mimetic triggers cerebral arteriopathy in juvenile brain via neutrophil elastase and NETosis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Dec, 2021 | Pubmed ID: 34293939
Microglia activation in postmortem brains with schizophrenia demonstrates distinct morphological changes between brain regions.
Brain pathology (Zurich, Switzerland) Jan, 2022 | Pubmed ID: 34297453
Administration of cyclic glycine-proline during infancy improves adult spatial memory, astrocyte plasticity, vascularization and GluR-1 expression in rats.
Nutritional neuroscience Dec, 2022 | Pubmed ID: 34565308
White matter injury but not germinal matrix hemorrhage induces elevated osteopontin expression in human preterm brains.
Acta neuropathologica communications Oct, 2021 | Pubmed ID: 34654477
Maternal n-3 Polyunsaturated Fatty Acid Enriched Diet Commands Fatty Acid Composition in Postnatal Brain and Protects from Neonatal Arterial Focal Stroke.
Translational stroke research Jun, 2022 | Pubmed ID: 34674145
N-Acetyl Cysteine Restores Sirtuin-6 and Decreases HMGB1 Release Following Lipopolysaccharide-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Mice.
Frontiers in cellular neuroscience , 2021 | Pubmed ID: 34867200
C3a Receptor Signaling Inhibits Neurodegeneration Induced by Neonatal Hypoxic-Ischemic Brain Injury.
Frontiers in immunology , 2021 | Pubmed ID: 34975856
Scavenger receptor CD36 governs recruitment of myeloid cells to the blood-CSF barrier after stroke in neonatal mice.
Journal of neuroinflammation Feb, 2022 | Pubmed ID: 35148760
Induction of Mitochondrial Fragmentation and Mitophagy after Neonatal Hypoxia-Ischemia.
Cells Apr, 2022 | Pubmed ID: 35406757
An Optimized and Detailed Step-by-Step Protocol for the Analysis of Neuronal Morphology in Golgi-Stained Fetal Sheep Brain.
Developmental neuroscience , 2022 | Pubmed ID: 35447627
Reelin cells and sex-dependent synaptopathology in autism following postnatal immune activation.
British journal of pharmacology Sep, 2022 | Pubmed ID: 35474185
Sex-Dependent Gliovascular Interface Abnormality in the Hippocampus following Postnatal Immune Activation in Mice.
Developmental neuroscience , 2022 | Pubmed ID: 35705008
Geometrical modelling of neuronal clustering and development.
Heliyon Jul, 2022 | Pubmed ID: 35847609
The Alpha 7 Nicotinic Acetylcholine Receptor Does Not Affect Neonatal Brain Injury.
Biomedicines Aug, 2022 | Pubmed ID: 36009570
Transcriptome network analysis links perinatal Staphylococcus epidermidis infection to microglia reprogramming in the immature hippocampus.
Glia Sep, 2023 | Pubmed ID: 37246946
Proteomics identifies lipocalin-2 in neonatal inflammation associated with cerebrovascular alteration in mice and preterm infants.
iScience Jul, 2023 | Pubmed ID: 37496672
Two different isoforms of osteopontin modulate myelination and axonal integrity.
FASEB bioAdvances Aug, 2023 | Pubmed ID: 37554545
Therapeutic Effect of Nicotinamide Mononucleotide for Hypoxic-Ischemic Brain Injury in Neonatal Mice.
ASN neuro , 2023 | Pubmed ID: 37787108
Immune-Neurovascular Interactions in Experimental Perinatal and Childhood Arterial Ischemic Stroke.
Stroke Feb, 2024 | Pubmed ID: 38252757
Long-term impact of maternal obesity on the gliovascular unit and ephrin signaling in the hippocampus of adult offspring.
Journal of neuroinflammation Feb, 2024 | Pubmed ID: 38308309
From hormones to behavior through microglial mitochondrial function.
Brain, behavior, and immunity Feb, 2024 | Pubmed ID: 38341051
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