Robert W. Sobol
Department of Pharmacology & Chemical Biology
University of Pittsburgh School of Medicine
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Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress.
Proceedings of the National Academy of Sciences of the United States of America May, 2002 | Pubmed ID: 11983862
Binary system for selective photoaffinity labeling of base excision repair DNA polymerases.
Nucleic acids research Jul, 2002 | Pubmed ID: 12136121
Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage.
DNA repair Apr, 2002 | Pubmed ID: 12509250
Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice.
DNA repair May, 2003 | Pubmed ID: 12713817
Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses.
The Journal of biological chemistry Oct, 2003 | Pubmed ID: 12882965
Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens.
Cancer research Sep, 2003 | Pubmed ID: 14522902
Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase.
The Journal of clinical investigation Jun, 2004 | Pubmed ID: 15199406
Cancer research Jul, 2005 | Pubmed ID: 16024643
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Jul, 2006 | Pubmed ID: 16849758
DNA repair Jan, 2007 | Pubmed ID: 16979388
The American journal of pathology Nov, 2006 | Pubmed ID: 17071602
Cancer research Mar, 2007 | Pubmed ID: 17332367
DNA repair Jun, 2007 | Pubmed ID: 17337257
Molecular cell Feb, 2008 | Pubmed ID: 18313379
Molecular pharmacology Aug, 2008 | Pubmed ID: 18477668
Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2008 | Pubmed ID: 18614692
Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice.
Biology of reproduction Nov, 2008 | Pubmed ID: 18650495
Proceedings of the National Academy of Sciences of the United States of America Jun, 2009 | Pubmed ID: 19520829
Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.
PloS one , 2009 | Pubmed ID: 19654874
BMC cancer , 2009 | Pubmed ID: 19807915
Carcinogenesis Dec, 2009 | Pubmed ID: 19864471
DNA polymerase beta-dependent long patch base excision repair in living cells.
DNA repair Feb, 2010 | Pubmed ID: 20006562
Molecular cancer research : MCR Jan, 2010 | Pubmed ID: 20068071
Mutation research Apr, 2010 | Pubmed ID: 20096707
Carcinogenesis May, 2010 | Pubmed ID: 20197299
Pediatric blood & cancer Dec, 2010 | Pubmed ID: 20589656
Antioxidants & redox signaling Jun, 2011 | Pubmed ID: 20649466
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Jan, 2011 | Pubmed ID: 20725730
BMC medical genomics , 2011 | Pubmed ID: 21269491
The Journal of biological chemistry Apr, 2011 | Pubmed ID: 21357694
Neuro-oncology May, 2011 | Pubmed ID: 21377995
Cancer research Mar, 2011 | Pubmed ID: 21406402
Cancer Apr, 2011 | Pubmed ID: 21425146
Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1.
Cancer research May, 2011 | Pubmed ID: 21444671
The base excision repair pathway is required for efficient lentivirus integration.
PloS one , 2011 | Pubmed ID: 21448280
XRCC1 and base excision repair balance in response to nitric oxide.
DNA repair Dec, 2011 | Pubmed ID: 22041025
Current molecular pharmacology Jan, 2012 | Pubmed ID: 22122465
Chemistry & biology Mar, 2012 | Pubmed ID: 22444586
Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitors.
Biochemistry Jul, 2012 | Pubmed ID: 22788932
Quantitative, Real-time Analysis of Base Excision Repair Activity in Cell Lysates Utilizing Lesion-specific Molecular Beacons
1Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine,
2Hillman Cancer Center, University of Pittsburgh Cancer Institute,
3Department of Experimental Therapy, The Netherlands Cancer Institute,
4Department of Human Genetics, University of Pittsburgh School of Public Health
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