Jingwu Xie

Activation of the hedgehog pathway in human hepatocellular carcinomas.

Novel mutations in the PATCHED gene in basal cell nevus syndrome.

IFNalpha induces Fas expression and apoptosis in hedgehog pathway activated BCC cells through inhibiting Ras-Erk signaling.

Activation of the hedgehog pathway in advanced prostate cancer.

Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of Fas expression and apoptosis.

CYP2E1 polymorphism, cigarette smoking, p53 expression, and survival in non-small cell lung cancer: a long term follow-up study.

Regulation of lung cancer cell growth and invasiveness by beta-TRCP.

Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas.

Hedgehog signaling is activated in subsets of esophageal cancers.

A mechanism of hyperthermia-induced apoptosis in ras-transformed lung cells.

Regulation of Gli1 localization by the cAMP/protein kinase A signaling axis through a site near the nuclear localization signal.

Activation of the hedgehog pathway in a subset of lung cancers.

Hedgehog signaling in prostate cancer.

Detoxification of olefinic epoxides and nucleotide excision repair of epoxide-mediated DNA damage: Insights from animal models examining human sensitivity to 1,3-butadiene.

Suppressing Wnt signaling by the hedgehog pathway through sFRP-1.

Loss of cell-adhesion molecule complexes in solid pseudopapillary tumor of pancreas.

Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells.

Molecular biology of basal and squamous cell carcinomas.

Hedgehog signaling pathway: development of antagonists for cancer therapy.

Implications of hedgehog signaling antagonists for cancer therapy.

Regulatory role of human AP-endonuclease (APE1/Ref-1) in YB-1-mediated activation of the multidrug resistance gene MDR1.

Protein kinase Cdelta negatively regulates hedgehog signaling by inhibition of Gli1 activity.

MEK1 mutations, but not ERK2 mutations, occur in melanomas and colon carcinomas, but none in thyroid carcinomas.

Activation of hedgehog signaling is not a frequent event in ovarian cancers.

Expression of hedgehog signaling molecules in lung cancer.

Requirement of TGFbeta signaling for SMO-mediated carcinogenesis.

Clinical implications of hedgehog signaling pathway inhibitors.

Identification of signature genes for detecting hedgehog pathway activation in esophageal cancer.

Role of fatty acid synthase in gemcitabine and radiation resistance of pancreatic cancers.

Hedgehog signaling in skin cancers.

Identification of signature genes for detecting hedgehog signaling activation in gastric cancer.

Uncommon GNAQ, MMP8, AKT3, EGFR, and PIK3R1 mutations in thyroid cancers.

Active sonic hedgehog signaling between androgen independent human prostate cancer cells and normal/benign but not cancer-associated prostate stromal cells.

Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling.

Rab23 negatively regulates Gli1 transcriptional factor in a Su(Fu)-dependent manner.

Activation of Hedgehog pathway in gastrointestinal cancers.

Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2.

Hedgehog signaling activation in the development of squamous cell carcinoma and adenocarcinoma of esophagus.

A role for transcription factor STAT3 signaling in oncogene smoothened-driven carcinogenesis.

Combining hedgehog signaling inhibition with focal irradiation on reduction of pancreatic cancer metastasis.