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Effects of perillyl alcohol on melanoma in the TPras mouse model.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Jun, 2002 | Pubmed ID: 12050099
Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient mice.
Cancer research Apr, 2004 | Pubmed ID: 15059911
Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers.
Archives of dermatology Jul, 2004 | Pubmed ID: 15262693
Neonatal ultraviolet radiation exposure is critical for malignant melanoma induction in pigmented Tpras transgenic mice.
The Journal of investigative dermatology Nov, 2005 | Pubmed ID: 16297212
The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation.
Cancer cell Dec, 2005 | Pubmed ID: 16338658
Melanocyte and keratinocyte carcinogenesis: p53 family protein activities and intersecting mRNA expression profiles.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research Nov, 2005 | Pubmed ID: 16363065
Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice.
Cancer research Mar, 2006 | Pubmed ID: 16540642
Skin hypoxia: a promoting environmental factor in melanomagenesis.
Cell cycle (Georgetown, Tex.) Jun, 2006 | Pubmed ID: 16760649
Cytotoxic activity of Apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma cell line.
Investigational new drugs Apr, 2007 | Pubmed ID: 17024575
Inhibition of phosphatidylinositol-3-kinase and mitogen-activated protein kinase kinase 1/2 prevents melanoma development and promotes melanoma regression in the transgenic TPRas mouse model.
Molecular cancer therapeutics Dec, 2006 | Pubmed ID: 17172409
Targeting integrins and PI3K/Akt-mediated signal transduction pathways enhances radiation-induced anti-angiogenesis.
Radiation research Jul, 2007 | Pubmed ID: 17722999
Notch1 is an effector of Akt and hypoxia in melanoma development.
The Journal of clinical investigation Nov, 2008 | Pubmed ID: 18924608
Hypoxia, melanocytes and melanoma - survival and tumor development in the permissive microenvironment of the skin.
Pigment cell & melanoma research Apr, 2009 | Pubmed ID: 19222803
Preformulation, formulation, and in vivo efficacy of topically applied apomine.
International journal of pharmaceutics Dec, 2009 | Pubmed ID: 19699284
Unique transforming properties of Notch1 in human melanocytes.
Pigment cell & melanoma research Dec, 2009 | Pubmed ID: 19708913
Integrin A6 Cleavage in Mouse Skin Tumors.
The open cancer journal Jan, 2008 | Pubmed ID: 20664806
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.
Pigment cell & melanoma research Dec, 2010 | Pubmed ID: 20849464
TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2012 | Pubmed ID: 23019362
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