Marianne Powell

Effects of perillyl alcohol on melanoma in the TPras mouse model.

Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient mice.

Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers.

Neonatal ultraviolet radiation exposure is critical for malignant melanoma induction in pigmented Tpras transgenic mice.

The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation.

Melanocyte and keratinocyte carcinogenesis: p53 family protein activities and intersecting mRNA expression profiles.

Spontaneous and UV radiation-induced multiple metastatic melanomas in Cdk4R24C/R24C/TPras mice.

Skin hypoxia: a promoting environmental factor in melanomagenesis.

Cytotoxic activity of Apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma cell line.

Inhibition of phosphatidylinositol-3-kinase and mitogen-activated protein kinase kinase 1/2 prevents melanoma development and promotes melanoma regression in the transgenic TPRas mouse model.

Targeting integrins and PI3K/Akt-mediated signal transduction pathways enhances radiation-induced anti-angiogenesis.

Notch1 is an effector of Akt and hypoxia in melanoma development.

Hypoxia, melanocytes and melanoma - survival and tumor development in the permissive microenvironment of the skin.

Preformulation, formulation, and in vivo efficacy of topically applied apomine.

Unique transforming properties of Notch1 in human melanocytes.

Integrin A6 Cleavage in Mouse Skin Tumors.

p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.

TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling.