Marie-Helene Metz-Boutigue

Mid-Membrane Photolabeling of the Transmembrane Domain of Glycophorin A in Phospholipid Vesicles This work was supported in part by the Japan Science and Technology Corporation (JST), the Université Louis Pasteur (ULP) "Supermolecules" Joint Research Project, and the European Union (DG-XII, contract PL 950990). We are grateful for support granted by JST to N.H., by the Herrmann-Schlosser Stiftung and the Stiftung zur Förderung Körperbehinderter to W.H., and by the "Société des Amis des Sciences" of France to P.G. We also thank Dr. F. Pattus, Dr. G. Crémel, Dr. P. Hubert, Dr. A. Van Dorsselaer (Strasbourg), Dr. J. L. Rigaud, and Dr. J. L. Popot (Paris) for stimulating discussions.

Regioselective photolabeling of glycoprotein A in membranes.

Protein trafficking to chromaffin granules and proteolytic processing within regulated secretory vesicles of neuroendocrine chromaffin cells.

Implication of endogenous morphine in the communication between neuroendocrine and immune systems.

The N- and C-terminal fragments of ubiquitin are important for the antimicrobial activities.

Different chromogranin immunoreactivity between prion and a-beta amyloid plaque.

Peptides from the N-terminal domain of chromogranin A (vasostatins) exert negative inotropic effects in the isolated frog heart.

The hippocampal cholinergic neurostimulating peptide, the N-terminal fragment of the secreted phosphatidylethanolamine-binding protein, possesses a new biological activity on cardiac physiology.

Effects of a chromogranin-derived peptide (CgA 47-66) in the writhing nociceptive response induced by acetic acid in rats.

Characterization and location of post-translational modifications on chromogranin B from bovine adrenal medullary chromaffin granules.

A role for chromogranin A (4-16), a vasostatin-derived peptide, on human colonic motility. An in vitro study.

The effect of a chromogranin A-derived peptide (CgA4-16) in the writhing nociceptive response induced by acetic acid in rats.

Effect of acetic acid or trypsin application on rat colonic motility in vitro and modulation by two synthetic fragments of chromogranin A.

Chromogranin A-derived peptides: interaction with the rat posterior cerebral artery.

Characterization of a morphine-like molecule in secretory granules of chromaffin cells.

Antifungal coating by biofunctionalized polyelectrolyte multilayered films.

Identification of morphine-6-glucuronide in chromaffin cell secretory granules.

Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine.

The emerging cardioinhibitory role of the hippocampal cholinergic neurostimulating peptide.

Rethinking the opiate system? Morphine and morphine-6-glucuronide as new endocrine and neuroendocrine mediators.

Characterization of natural vasostatin-containing peptides in rat heart.

Enhanced membrane disruption and antibiotic action against pathogenic bacteria by designed histidine-rich peptides at acidic pH.

Variability in secondary structure of the antimicrobial peptide Cateslytin in powder, solution, DPC micelles and at the air-water interface.

Endogenous morphine in SH-SY5Y cells and the mouse cerebellum.

Aggregation of cateslytin beta-sheets on negatively charged lipids promotes rigid membrane domains. A new mode of action for antimicrobial peptides?

Prognostic value of chromogranin A at admission in critically ill patients: a cohort study in a medical intensive care unit.

Serum concentration of chromogranin A at admission: an early biomarker of severity in critically ill patients.

Structural determinants of antimicrobial and antiplasmodial activity and selectivity in histidine-rich amphipathic cationic peptides.

Two chromogranin a-derived peptides induce calcium entry in human neutrophils by calmodulin-regulated calcium independent phospholipase A2.

Characterization of human and bovine phosphatidylethanolamine-binding protein (PEBP/RKIP) interactions with morphine and morphine-glucuronides determined by noncovalent mass spectrometry.

Cytoskeleton mediates negative inotropism and lusitropism of chromogranin A-derived peptides (human vasostatin1-78 and rat CgA₁₋₆₄) in the rat heart.

The antimicrobial peptides derived from chromogranin/secretogranin family, new actors of innate immunity.

Antimicrobial peptides present in mammalian skin and gut are multifunctional defence molecules.

Catestatin, an endogenous chromogranin A-derived peptide, inhibits in vitro growth of Plasmodium falciparum.

Endogenous morphine levels are increased in sepsis: a partial implication of neutrophils.

Membrane structure and interactions of human catestatin by multidimensional solution and solid-state NMR spectroscopy.

Role of vasostatin-1 C-terminal region in fibroblast cell adhesion.

Granins--peptides derived from the secretory proteins.

Cyto-mechanoresponsive polyelectrolyte multilayer films.

Comparison of serum and lithium-heparinate plasma for the accurate measurements of endogenous and exogenous morphine concentrations.

Modification of macroporous titanium tracheal implants with biodegradable structures: tracking in vivo integration for determination of optimal in situ epithelialization conditions.

Development of an immunoassay for the derived-peptide of chromogranin A, vasostatin-I (1-76): assessment of severity in patients with sepsis.

Vasostatin-I, a chromogranin A-derived peptide, in non-selected critically ill patients: distribution, kinetics, and prognostic significance.

Stretch-induced biodegradation of polyelectrolyte multilayer films for drug release.

Systemic Down-Regulation of Delta-9 Desaturase Promotes Muscle Oxidative Metabolism and Accelerates Muscle Function Recovery following Nerve Injury.