Laboratory of Metabolism,
National Cancer Institute,
Laboratory of Metabolism, National Cancer Institute,
National Cancer Institute, Laboratory of Metabolism
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Secretoglobin 3A2/uteroglobin-related protein 1 is a novel marker for pulmonary carcinoma in mice and humans.
Lung cancer (Amsterdam, Netherlands) Jan, 2011 | Pubmed ID: 20466451
A polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma.
American journal of human genetics Mar, 2002 | Pubmed ID: 11813133
Increased expression of thyroid transcription factor-1 (TTF-1) in respiratory epithelial cells inhibits alveolarization and causes pulmonary inflammation.
Developmental biology Feb, 2002 | Pubmed ID: 11820807
Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice.
The Journal of clinical investigation Feb, 2002 | Pubmed ID: 11854318
Pituitary hormones are not required for sexual differentiation of male mice: phenotype of the T/ebp/Nkx2.1 null mutant mice.
Endocrinology Nov, 2002 | Pubmed ID: 12399445
Study of P450 function using gene knockout and transgenic mice.
Archives of biochemistry and biophysics Jan, 2003 | Pubmed ID: 12464254
Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2.
Carcinogenesis Mar, 2003 | Pubmed ID: 12663521
Microarray analysis using amplified mRNA from laser capture microdissection of microscopic hepatocellular precancerous lesions and frozen hepatocellular carcinomas reveals unique and consistent gene expression profiles.
Toxicologic pathology May-Jun, 2003 | Pubmed ID: 12746117
Aberrant trajectory of ascending dopaminergic pathway in mice lacking Nkx2.1.
Experimental neurology Jul, 2003 | Pubmed ID: 12821380
Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor.
Molecular endocrinology (Baltimore, Md.) Nov, 2003 | Pubmed ID: 12907760
[Homeodomain transcription factor T/EBP/NKX2.1 in development and differentiation of the thyroid and lung].
Seikagaku. The Journal of Japanese Biochemical Society Dec, 2003 | Pubmed ID: 14748143
In vivo characterization of the Nkx2.1 promoter/enhancer elements in transgenic mice.
Gene Apr, 2004 | Pubmed ID: 15094193
Thyrocyte-specific expression of Cre recombinase in transgenic mice.
Genesis (New York, N.Y. : 2000) Jul, 2004 | Pubmed ID: 15282748
Developmental regulation of claudin localization by fetal alveolar epithelial cells.
American journal of physiology. Lung cellular and molecular physiology Dec, 2004 | Pubmed ID: 15347569
Interleukin-10 induces uteroglobin-related protein (UGRP) 1 gene expression in lung epithelial cells through homeodomain transcription factor T/EBP/NKX2.1.
The Journal of biological chemistry Dec, 2004 | Pubmed ID: 15485815
Decreased expression of uteroglobin-related protein 1 in inflamed mouse airways is mediated by IL-9.
American journal of physiology. Lung cellular and molecular physiology Dec, 2004 | Pubmed ID: 15531759
Progressive glomerulonephritis and histiocytic sarcoma associated with macrophage functional defects in CYP1B1-deficient mice.
Toxicologic pathology Nov-Dec, 2004 | Pubmed ID: 15580705
An integrated regulatory network controlling survival and migration in thyroid organogenesis.
Developmental biology Dec, 2004 | Pubmed ID: 15581879
Interleukin-5 reduces the expression of uteroglobin-related protein (UGRP) 1 gene in allergic airway inflammation.
Immunology letters Feb, 2005 | Pubmed ID: 15626484
Induction of uteroglobin-related protein 2 (Ugrp2) expression by EGF and TGFalpha.
FEBS letters Apr, 2005 | Pubmed ID: 15811345
Ventromedial hypothalamic nucleus-specific enhancer of Ad4BP/SF-1 gene.
Molecular endocrinology (Baltimore, Md.) Nov, 2005 | Pubmed ID: 15994202
A mouse model demonstrates a multigenic origin of congenital hypothyroidism.
Endocrinology Dec, 2005 | Pubmed ID: 16150900
Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2.
Chemical research in toxicology Sep, 2005 | Pubmed ID: 16167840
Induction of uteroglobin-related protein 2 (Ugrp2) gene expression by the Th2 cytokines IL-4 and IL-13.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2005 | Pubmed ID: 16237061
Directed differentiation of neural cells to hypothalamic dopaminergic neurons.
Development (Cambridge, England) Dec, 2005 | Pubmed ID: 16284116
Origin of the ultimobranchial body cyst: T/ebp/Nkx2.1 expression is required for development and fusion of the ultimobranchial body to the thyroid.
Developmental dynamics : an official publication of the American Association of Anatomists May, 2006 | Pubmed ID: 16342117
Alterations in skin and stratified epithelia by constitutively activated PPARalpha.
The Journal of investigative dermatology Feb, 2006 | Pubmed ID: 16374467
Uteroglobin-related protein 1 expression suppresses allergic airway inflammation in mice.
American journal of respiratory and critical care medicine May, 2006 | Pubmed ID: 16456148
A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes.
Molecular pharmacology Jun, 2006 | Pubmed ID: 16505155
Hop functions downstream of Nkx2.1 and GATA6 to mediate HDAC-dependent negative regulation of pulmonary gene expression.
American journal of physiology. Lung cellular and molecular physiology Aug, 2006 | Pubmed ID: 16510470
Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid.
Molecular endocrinology (Baltimore, Md.) Aug, 2006 | Pubmed ID: 16601074
Regulation of mouse hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepatocyte nuclear factor 4alpha and peroxisome proliferator-activated receptor alpha.
Molecular pharmacology Oct, 2006 | Pubmed ID: 16807375
Peroxisome proliferator-activated receptor alpha activation during pregnancy severely impairs mammary lobuloalveolar development in mice.
Endocrinology Oct, 2006 | Pubmed ID: 16857745
Identification and expression of alternative splice variants of the mouse Ppp1r3b gene in lung epithelial cells.
Biochemical and biophysical research communications Oct, 2006 | Pubmed ID: 16949035
GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo.
Development (Cambridge, England) Jan, 2007 | Pubmed ID: 17164424
Deletion of the Ttf1 gene in differentiated neurons disrupts female reproduction without impairing basal ganglia function.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2006 | Pubmed ID: 17182767
A comprehensive investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism in the mouse using a multivariate data analysis approach.
Chemical research in toxicology Mar, 2007 | Pubmed ID: 17279779
Pten loss in the mouse thyroid causes goiter and follicular adenomas: insights into thyroid function and Cowden disease pathogenesis.
Cancer research Feb, 2007 | Pubmed ID: 17283127
Side population cells in the mouse thyroid exhibit stem/progenitor cell-like characteristics.
Endocrinology Sep, 2007 | Pubmed ID: 17584961
Plasma UGRP1 levels associate with promoter G-112A polymorphism and the severity of asthma.
Allergology international : official journal of the Japanese Society of Allergology Mar, 2008 | Pubmed ID: 18089940
Regulation of mouse Scgb3a1 gene expression by NF-Y and association of CpG methylation with its tissue-specific expression.
BMC molecular biology , 2008 | Pubmed ID: 18194566
Role of secretoglobin 3A2 in lung development.
American journal of respiratory and critical care medicine Aug, 2008 | Pubmed ID: 18535256
CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression.
The Journal of biological chemistry Sep, 2008 | Pubmed ID: 18632661
The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes.
Neuron Sep, 2008 | Pubmed ID: 18786356
Postmitotic Nkx2-1 controls the migration of telencephalic interneurons by direct repression of guidance receptors.
Neuron Sep, 2008 | Pubmed ID: 18786357
Oncostatin M regulates secretoglobin 3A1 and 3A2 expression in a bidirectional manner.
American journal of respiratory cell and molecular biology May, 2009 | Pubmed ID: 18978304
IFN-gamma down-regulates Secretoglobin 3A1 gene expression.
Biochemical and biophysical research communications Feb, 2009 | Pubmed ID: 19135978
Expression of secretoglobin3A2 (SCGB3A2) in primary pulmonary carcinomas.
Fukushima journal of medical science Dec, 2008 | Pubmed ID: 19418968
Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice.
Carcinogenesis Sep, 2009 | Pubmed ID: 19581346
The proximal STAT6 and NF-kappaB sites are responsible for IL-13- and TNF-alpha-induced RhoA transcriptions in human bronchial smooth muscle cells.
Pharmacological research May, 2010 | Pubmed ID: 20006706
The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2010 | Pubmed ID: 20181579
Identification and characterization of rat RhoA gene promoter.
Journal of pharmacological sciences , 2010 | Pubmed ID: 20308800
Development of thyroid gland and ultimobranchial body cyst is independent of p63.
Laboratory investigation; a journal of technical methods and pathology Jan, 2011 | Pubmed ID: 20697379
A functional interaction between CPI-17 and RACK1 proteins in bronchial smooth muscle cells.
Biochemical and biophysical research communications Oct, 2010 | Pubmed ID: 20875397
Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2011 | Pubmed ID: 21220306
FOXA1 plays a role in regulating secretoglobin 1a1 expression in the absence of CCAAT/enhancer binding protein activities in lung in vivo.
American journal of physiology. Lung cellular and molecular physiology Mar, 2011 | Pubmed ID: 21224212
Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation.
The Journal of biological chemistry Jun, 2011 | Pubmed ID: 21478551
Experience dictates stem cell fate in the adult hippocampus.
Neuron Jun, 2011 | Pubmed ID: 21658584
Thyroid-specific transcription factors and their roles in thyroid cancer.
Journal of thyroid research , 2011 | Pubmed ID: 21687604
Wnt/β-catenin signaling pathway is a direct enhancer of thyroid transcription factor-1 in human papillary thyroid carcinoma cells.
PloS one , 2011 | Pubmed ID: 21814573
Conditional deletion of insulin receptor in thyrocytes does not affect thyroid structure and function.
Endocrine journal , 2011 | Pubmed ID: 21908931
The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1.
The European journal of neuroscience Dec, 2011 | Pubmed ID: 22098391
Thyroid-specific knockout of the tumor suppressor mitogen-inducible gene 6 activates epidermal growth factor receptor signaling pathways and suppresses nuclear factor-κB activity.
Surgery Dec, 2011 | Pubmed ID: 22136853
Thyroid regeneration: characterization of clear cells after partial thyroidectomy.
Endocrinology May, 2012 | Pubmed ID: 22454152
Soluble vascular adhesion protein-1 accumulates in proliferative diabetic retinopathy.
Investigative ophthalmology & visual science Jun, 2012 | Pubmed ID: 22618595
Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2012 | Pubmed ID: 22797898
Deficiency of CCAAT/enhancer binding protein family DNA binding prevents malignant conversion of adenoma to carcinoma in NNK-induced lung carcinogenesis in the mouse.
Molecular cancer , 2012 | Pubmed ID: 23234329
Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.
Molecular cell Apr, 2013 | Pubmed ID: 23523371
Noninvasive monitoring of pulmonary fibrosis by targeting matrix metalloproteinases (MMPs).
Molecular pharmaceutics Jun, 2013 | Pubmed ID: 23607644
Postnatal expression of BRAFV600E does not induce thyroid cancer in mouse models of thyroid papillary carcinoma.
Endocrinology Nov, 2013 | Pubmed ID: 23970782
Preclinical evaluation of human secretoglobin 3A2 in mouse models of lung development and fibrosis.
American journal of physiology. Lung cellular and molecular physiology Jan, 2014 | Pubmed ID: 24213919
Stem cell antigen 1-positive mesenchymal cells are the origin of follicular cells during thyroid regeneration.
PloS one , 2013 | Pubmed ID: 24278321
Molecular cloning and functional characterization of two forms of Pax8 in the rainbow trout, Oncorhynchus mykiss.
General and comparative endocrinology Mar, 2014 | Pubmed ID: 24380675
Regulation of LH/FSH expression by secretoglobin 3A2 in the mouse pituitary gland.
Cell and tissue research Apr, 2014 | Pubmed ID: 24514953
Thyroid regeneration: how stem cells play a role?
Frontiers in endocrinology , 2014 | Pubmed ID: 24782833
Secretoglobin superfamily protein SCGB3A2 deficiency potentiates ovalbumin-induced allergic pulmonary inflammation.
Mediators of inflammation , 2014 | Pubmed ID: 25242865
Activation of intestinal human pregnane X receptor protects against azoxymethane/dextran sulfate sodium-induced colon cancer.
The Journal of pharmacology and experimental therapeutics Dec, 2014 | Pubmed ID: 25277138
Expression of stanniocalcin 1 in thyroid side population cells and thyroid cancer cells.
Thyroid : official journal of the American Thyroid Association Apr, 2015 | Pubmed ID: 25647164
SCGB3A2 Inhibits Acrolein-Induced Apoptosis through Decreased p53 Phosphorylation.
Acta histochemica et cytochemica Apr, 2015 | Pubmed ID: 26019375
Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans.
Gastroenterology Oct, 2015 | Pubmed ID: 26099526
KRAS(G12D)-mediated oncogenic transformation of thyroid follicular cells requires long-term TSH stimulation and is regulated by SPRY1.
Laboratory investigation; a journal of technical methods and pathology Jul, 2015 | Pubmed ID: 26146959
Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice.
BMC pulmonary medicine , 2015 | Pubmed ID: 26178733
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