Stella E. Tsirka

Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator.

Tissue plasminogen activator mediates microglial activation via its finger domain through annexin II.

Extracellular proteases and neuronal cell death.

Tissue plasminogen activator as a modulator of neuronal survival and function.

Microglial activation and recruitment, but not proliferation, suffice to mediate neurodegeneration.

Involvement of tissue plasminogen activator in onset and effector phases of experimental allergic encephalomyelitis.

Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury.

Protective role of tuftsin fragment 1-3 in an animal model of intracerebral hemorrhage.

Modulation of zinc toxicity by tissue plasminogen activator.

Increased expression of two phospholipase D isoforms during experimentally induced hippocampal mossy fiber outgrowth.

Tissue plasminogen activator and glial function.

Tuftsin fragment 1-3 is beneficial when delivered after the induction of intracerebral hemorrhage.

Phospholipase D1-promoted release of tissue plasminogen activator facilitates neurite outgrowth.

Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage.

Fibrin-modifying serine proteases thrombin, tPA, and plasmin in ischemic stroke: a review.

Contribution of extracellular proteolysis and microglia to intracerebral hemorrhage.

PET imaging of glucose metabolism in a mouse model of temporal lobe epilepsy.

Nitric oxide mediates neurodegeneration and breakdown of the blood-brain barrier in tPA-dependent excitotoxic injury in mice.

Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice.

Nitric oxide synthase isoforms undertake unique roles during excitotoxicity.

Brain edema after intracerebral hemorrhage: mechanisms, treatment options, management strategies, and operative indications.

Modulation of microglial/macrophage activation by macrophage inhibitory factor (TKP) or tuftsin (TKPR) attenuates the disease course of experimental autoimmune encephalomyelitis.

A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator.

tPA-mediated generation of plasmin is catalyzed by the proteoglycan NG2.

Tissue-type plasminogen activator as a therapeutic target in stroke.

Endothelial NOS-deficient mice reveal dual roles for nitric oxide during experimental autoimmune encephalomyelitis.

Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA-/-) mice.

Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice.

Tissue plasminogen activator alters intracellular sequestration of zinc through interaction with the transporter ZIP4.

The C terminus of mouse monocyte chemoattractant protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency.

Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis.

Microglia/macrophages promote glioma progression.

Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption.

Mouse MCP1 C-terminus inhibits human MCP1-induced chemotaxis and BBB compromise.

Annexin A2 promotes glioma cell invasion and tumor progression.

Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system.

Animal Models of MS Reveal Multiple Roles of Microglia in Disease Pathogenesis.

The CCL2-CCR2 system affects the progression and clearance of intracerebral hemorrhage.

Quantification of particle-induced inflammatory stress response: a novel approach for toxicity testing of earth materials.

Tuftsin promotes an anti-inflammatory switch and attenuates symptoms in experimental autoimmune encephalomyelitis.

Microglial inhibitory factor (MIF/TKP) mitigates secondary damage following spinal cord injury.

p53 opens the mitochondrial permeability transition pore to trigger necrosis.

Inflammation modulates expression of laminin in the central nervous system following ischemic injury.

Neuroimaging in Animal Seizure Models with (18)FDG-PET.

The annexin A2/S100A10 system in health and disease: emerging paradigms.

Microglia actively regulate the number of functional synapses.

Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells.

Inflammatory stress response in A549 cells as a result of exposure to coal: Evidence for the role of pyrite in coal workers' pneumoconiosis pathogenesis.