Kyoto university
2 ARTICLES PUBLISHED IN JoVE
Medicine
Orthotopic Small Bowel Transplantation in Rats
Koji Kitamura *1,2, Martin W. von Websky *1, Ichiro Ohsawa 1, Azin Jaffari 1, Thomas C. Pech 1, Tim Vilz 1, Sven Wehner 1, Shinji Uemoto 2, Joerg C. Kalff 1, Nico Schaefer 1
1Department of Surgery, University of Bonn, Germany, 2Department of Surgery, Kyoto University Hospital
Small bowel transplantation has become an accepted treatment option for patients with irreversible intestinal failure. Our experimental model of orthotopic small bowel transplantation in rats serves as a reliable tool to address underlying immunologic and inflammatory processes that complicate intestinal transplantation.
Medicine
Surgical Procedures for a Rat Model of Partial Orthotopic Liver Transplantation with Hepatic Arterial Reconstruction
Kazuyuki Nagai 1,2, Shintaro Yagi 2, Shinji Uemoto 2, Rene H. Tolba 1
1Institute for Laboratory Animal Science and Experimental Surgery, RWTH-Aachen University, 2Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Graduate School of Medicine, Kyoto University
Orthotopic liver transplantation in rats is an indispensable experimental model for biomedical research. Here we present our surgical procedures for orthotopic rat liver transplantation with hepatic arterial reconstruction using a 50% partial graft.
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