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Asahikawa Medical University

1 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Engineering of Human Blood-Induced Microglia-like Cells for Reverse-Translational Brain Research

Sota Kyuragi^*1, Shogo Inamine^*1, Masahiro Ohgidani^1,2, Takahiro A. Kato¹

¹Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, ²Department of Functional Anatomy and Neuroscience, Asahikawa Medical University

This study delineates a novel approach for the establishment of human monocyte-derived microglia-like (iMG) cells that enable the indirect assessment of brain inflammation. This presents a cellular model that may be beneficial to research focusing on potential inflammation of the brain and associated neuropsychiatric disorders.