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University of Nebraska at Lincoln

1 ARTICLES PUBLISHED IN JoVE

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Immunology and Infection

Protein Misfolding Cyclic Amplification of Prions
Samuel E. Saunders 1, Jason C. Bartz 2, Ronald A. Shikiya 2
1Department of Civil Engineering, University of Nebraska at Lincoln, 2Department of Medical Microbiology and Immunology, Creighton University

Protein misfolding cyclic amplification (PMCA) is an in vitro assay for the study of prion conversion and strain and species barriers. It can also be used as a prion detection assay.

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