Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering ChamberWeiqing Zhan *1, Diego Marre *1, Geraldine M. Mitchell 1,2,3, Wayne A. Morrison 1,2,3, Shiang Y. Lim 1,2
1O'Brien Institute Department, St Vincent's Institute of Medical Research, 2Department of Surgery, University of Melbourne, 3Faculty of Health Sciences, Australia Catholic University
This is a guideline for constructing in vivo vascularized tissue using a microsurgical arteriovenous loop or a flow-through pedicle configuration inside a tissue engineering chamber. The vascularized tissues generated can be employed for organ regeneration and replacement of tissue defects, as well as for drug testing and disease modeling.
