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Klinikum Chemnitz gGmbH

2 ARTICLES PUBLISHED IN JoVE

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Medicine

Monitoring of Systemic and Hepatic Hemodynamic Parameters in Mice
Chichi Xie 1,3, Weiwei Wei 1, Tao Zhang 1, Olaf Dirsch 2, Uta Dahmen 1
1Department of General, Visceral and Vascular Surgery, Jena University Hospital, 2Institute of Pathology, Jena University Hospital, 3Reproductive Medicine Center, The First Affiliated Hospital of Wenzhou Medical University

This film demonstrates how to acquire systemic and hepatic hemodynamics in mice. The whole monitoring includes acquisition of vital parameters, systemic blood pressure, central venous pressure, common hepatic artery flow rate, and portal vein pressure as well as the portal flow rate in mice.

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Medicine

Visualization of Vascular and Parenchymal Regeneration after 70% Partial Hepatectomy in Normal Mice
Chichi Xie 1, Weiwei Wei 1, Andrea Schenk 3, Lars Ole Schwen 3, Sara Zafarnia 2, Michael Schwier 3, Felix Gremse 2, Isabel Jank 1, Olaf Dirsch 4, Uta Dahmen 1
1Department of General, Visceral and Vascular Surgery, Jena University Hospital, 2Experimental Molecular Imaging, RWTH Aachen University, 3Fraunhofer Institute for Medical Image Computing MEVIS, 4Institute of Pathology, Klinikum Chemnitz gGmbH

Tools used for visualizing vascular regeneration require methods for contrasting the vascular trees. This film demonstrated a delicate injection technique used to achieve optimal contrasting of the vascular trees and illustrate the potential benefits resulting from a detailed analysis of the resulting specimen using µCT and histological serial sections.

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