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Nicolaus Copernicus University in Torun

2 ARTICLES PUBLISHED IN JoVE

Medicine

Using a Chemical Biopsy for Graft Quality Assessment

Iga Stryjak^*1, Natalia Warmuzińska^*1, Kamil Łuczykowski¹, Matyas Hamar², Peter Urbanellis², Emilia Wojtal³, Marek Masztalerz³, Markus Selzner^2,4, Zbigniew Włodarczyk³, Barbara Bojko¹

¹Department of Pharmacodynamics and Molecular Pharmacology, Faculty of Pharmacy, Nicolaus Copernicus University in Torun, Collegium Medicum in Bydgoszcz, ²Multi Organ Transplant Program, Department of Surgery, Toronto General Hospital, University Health Network, ³Department of Transplantology and General Surgery, Collegium Medicum in Bydgoszcz, Antoni Jurasz University Hospital No. 1 in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland, ⁴Department of Medicine, Toronto General Hospital

The protocol presents utilization of the chemical biopsy approach followed by comprehensive metabolomic and lipidomic analysis for quality assessment of kidney grafts allocated for transplantation.

Medicine

On-Site Sampling and Extraction of Brain Tumors for Metabolomics and Lipidomics Analysis

Joanna Bogusiewicz^*1, Paulina Zofia Goryńska^*1, Magdalena Gaca¹, Kamila Chmara¹, Krzysztof Goryński¹, Karol Jaroch¹, Dariusz Paczkowski², Jacek Furtak², Marek Harat^2,3, Barbara Bojko¹

¹Department of Pharmacodynamics and Molecular Pharmacology, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, ²Department of Neurosurgery, 10th Military Research Hospital and Polyclinic, ³Division of Preventive Medicine and Healthy Policy, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun

The manuscript presents on-site sampling of human brain tumors with solid phase microextraction followed by their biochemical profiling towards the discovery of biomarkers.