Asklepios Klinik St. Georg
2 ARTICLES PUBLISHED IN JoVE
Medicine
Training a Sophisticated Microsurgical Technique: Interposition of External Jugular Vein Graft in the Common Carotid Artery in Rats
Karina Schleimer 1, Jochen Grommes 1, Andreas Greiner 1, Houman Jalaie 1, Johannes Kalder 1, Stephan Langer 1, Thomas A. Koeppel 1, Michael Jacobs 1, Maria Kokozidou 1
1European Vascular Center Aachen-Maastricht, Department of Vascular Surgery, University Hospital RWTH Aachen
Neointimal hyperplasia is the primary cause of stenosis in arterialized veins. We propose a new protocol whereby the right external jugular vein is grafted using the cuff technique in the common carotid artery of Sprague Dawley rats. The survival rate was 100 % at the time point of sacrifice.
Medicine
Using the Sleeve Technique in a Mouse Model of Aortic Transplantation - An Instructional Video
Zuzanna Rowinska 1,2, Simone Gorressen 3, Marc W. Merx 4, Thomas A. Koeppel 5, Alma Zernecke 6, Elisa A. Liehn 2
1Department of Vascular Surgery and Interdisciplinary Vein Center, St. Josef-Hospital, Ruhr- University Bochum, 2Institute of Molecular Cardiovascular Research, University Hospital, RWTH Aachen University Department of Medicine, 3Institute of Pharmacology and Clinical Pharmacology, Düsseldorf University Hospital, 4Department of Cardiology, Vascular Medicine and Intensive Care Medicine, Hospital Robert Koch Gehrden, 5Division of Vascular Surgery, Asklepios Klinik St. Georg, 6Institute of Experimental Biomedicine, Würzburg University
We present an orthotopic aortic transplantation model using the sleeve technique in mice. It is a very rapid anastomosis method, which can be employed in studies of vascular disease.
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