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Asklepios Klinik St. Georg

2 ARTICLES PUBLISHED IN JoVE

Medicine

Training a Sophisticated Microsurgical Technique: Interposition of External Jugular Vein Graft in the Common Carotid Artery in Rats

Karina Schleimer¹, Jochen Grommes¹, Andreas Greiner¹, Houman Jalaie¹, Johannes Kalder¹, Stephan Langer¹, Thomas A. Koeppel¹, Michael Jacobs¹, Maria Kokozidou¹

¹European Vascular Center Aachen-Maastricht, Department of Vascular Surgery, University Hospital RWTH Aachen

Neointimal hyperplasia is the primary cause of stenosis in arterialized veins. We propose a new protocol whereby the right external jugular vein is grafted using the cuff technique in the common carotid artery of Sprague Dawley rats. The survival rate was 100 % at the time point of sacrifice.

Medicine

Using the Sleeve Technique in a Mouse Model of Aortic Transplantation - An Instructional Video

Zuzanna Rowinska^1,2, Simone Gorressen³, Marc W. Merx⁴, Thomas A. Koeppel⁵, Alma Zernecke⁶, Elisa A. Liehn²

¹Department of Vascular Surgery and Interdisciplinary Vein Center, St. Josef-Hospital, Ruhr- University Bochum, ²Institute of Molecular Cardiovascular Research, University Hospital, RWTH Aachen University Department of Medicine, ³Institute of Pharmacology and Clinical Pharmacology, Düsseldorf University Hospital, ⁴Department of Cardiology, Vascular Medicine and Intensive Care Medicine, Hospital Robert Koch Gehrden, ⁵Division of Vascular Surgery, Asklepios Klinik St. Georg, ⁶Institute of Experimental Biomedicine, Würzburg University

We present an orthotopic aortic transplantation model using the sleeve technique in mice. It is a very rapid anastomosis method, which can be employed in studies of vascular disease.