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NASA/SSERVI's Institute for Modeling Plasma, Atmospheres and Cosmic Dust

3 ARTICLES PUBLISHED IN JoVE

Environment

Experimental Methods of Dust Charging and Mobilization on Surfaces with Exposure to Ultraviolet Radiation or Plasmas

Xu Wang^1,2, Joseph Schwan^1,2, Noah Hood^1,2, Hsiang-Wen Hsu^1,2, Eberhard Grün^1,2, Mihály Horányi^1,2

¹Laboratory for Atmospheric and Space Physics, University of Colorado, ²NASA/SSERVI's Institute for Modeling Plasma, Atmospheres and Cosmic Dust

Dust charging and mobilization is demonstrated in three experiments with exposure to thermal plasma with beam electrons, beam electrons only, or ultraviolet (UV) radiation only. These experiments present the advanced understanding of electrostatic dust transport and its role in shaping the surfaces of airless planetary bodies.

Neuroscience

A Rat Model of Central Fatigue Using a Modified Multiple Platform Method

Weiyue Zhang^*1, Wei Zhang^*1, Ning Dai^*1, Chenxia Han², Fengzhi Wu¹, Xu Wang¹, Libo Tan¹, Jie Li¹, Feng Li¹, Qingjia Ren³

¹School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, ²Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, ³Institute of Tibetan Medicine, Tibetan Traditional Medical College

Here, we present a protocol to introduce a rat model of central fatigue using the modified multiple platform method (MMPM).

Cancer Research

Patient-derived Heterogeneous Xenograft Model of Pancreatic Cancer Using Zebrafish Larvae as Hosts for Comparative Drug Assessment

Lei Wang^*1, Huan Chen^*2,3, Fei Fei^*1, Xianfeng He^2,3, Shaoyang Sun¹, Kunpeng Lv¹, Bo Yu^2,3, Jiang Long^2,4,5,6, Xu Wang¹

¹Department of Biochemistry and Molecular Biology, Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, School of Basic Medical Sciences, Fudan University, ²National Human Genetic Resources Sharing Service Platform (2005DKA21300), ³Fudan University Shanghai Cancer Center, ⁴Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, ⁵Department of Oncology, Shanghai Medical College, Fudan University, ⁶Pancreatic Cancer Institute, Fudan University

This protocol describes optimization procedures in a virus-based dual fluorescence-labeled tumor xenograft model using larval zebrafish as hosts. This heterogeneous xenograft model mimics the tissue composition of pancreatic cancer microenvironment in vivo and serves as a more precise tool for assessing drug responses in personalized zPDX (zebrafish patient-derived xenograft) models.