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Ludwig Boltzmann Institute for Cancer Research (LBI-CR)

1 ARTICLES PUBLISHED IN JoVE

Cancer Research

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Herwig P. Moll¹, Julian Mohrherr², Kristina Breitenecker², Marcel Haber², Viktor Voronin², Emilio Casanova^1,2

¹Department of Physiology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna, ²Ludwig Boltzmann Institute for Cancer Research (LBI-CR)

Here we describe a minimally invasive syngeneic orthotopic transplantation model of mouse lung adenocarcinoma cells as a time- and cost-reducing model to study non-small cell lung cancer.