After performing the dose-response experiment, use surgical scissors to cut the microdialysis probes. Carefully remove the laser doppler flowmetry probes from the heaters and detach the heaters from the skin. Gently remove the tape securing the probes to the skin.
Inspect the puncture sites on either side of the probe to identify the smallest blood clot. Cut the probe near the site with the smaller clot, leaving approximately one inch of the probe outside the skin uncut. Then clean the skin area around the probe's entry and exit sites using an alcohol swab, including the one-inch length on the less-clotted side.
Grasp the probe extending from the puncture site with the larger clot and gently pull it towards the clot. Lastly, cover any bleeding from the probe's removal with sterile gauze and apply pressure.
