To measure the cornea tear smoothness, place the rat under a stereomicroscope, equipped with a ring illuminator and a camera. Then, apply 5 microliters of saline to the rat cornea. With gloved fingers, passively blink by moving the upper and lower eyelids approximately five times to spread the saline. Under 1.6 times magnification, focus the ring illuminator on the middle of the cornea surface, then, after 10 seconds, acquire photographic images.
Intense Pulsed Light for the Treatment of Dry Eye Owing to Meibomian Gland Dysfunction
A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies
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