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Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex

DOI :

10.3791/3802-v

March 28th, 2012

March 28th, 2012

15,399 Views

1Neuroinformatics DTC, University of Edinburgh , 2Centre for Integrative Physiology, University of Edinburgh

We describe procedures for preparation and electrophysiological recording from brain slices that maintain the dorsal-ventral axis of the medial entorhinal cortex (MEC). Because neural encoding of location follows a dorsal-ventral organization within the MEC, these procedures facilitate investigation of cellular mechanisms important for navigation and memory.

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Parasagittal Slices

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