JoVE Logo
Faculty Resource Center

Sign In

Methods for Studying the Mechanisms of Action of Antipsychotic Drugs in Caenorhabditis elegans

DOI :

10.3791/50864-v

February 4th, 2014

February 4th, 2014

11,312 Views

1Department of Psychiatry, Harvard Medical School, 2Mailman Research Center, McLean Hospital

Approaches for testing the effects of antipsychotic drugs (APDs) in Caenorhabditis elegans are demonstrated. Assays are described for testing drug effects on development and viability and on pharyngeal pumping rate. These methods are also applicable for pharmacogenetic experiments with drug classes other than APDs.

Tags

Caenorhabditis Elegans

-- Views

Related Videos

article

Mouse in Utero Electroporation: Controlled Spatiotemporal Gene Transfection

article

Direct Intraventricular Delivery of Drugs to the Rodent Central Nervous System

article

A Caenorhabditis elegans Model System for Amylopathy Study

article

Whole Mount Immunolabeling of Olfactory Receptor Neurons in the Drosophila Antenna

article

An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans

article

Agarose Microchambers for Long-term Calcium Imaging of Caenorhabditis elegans

article

Novel Metrics to Characterize Embryonic Elongation of the Nematode Caenorhabditis elegans

article

A Caenorhabditis elegans Nutritional-status Based Copper Aversion Assay

article

Ratiometric Calcium Imaging of Individual Neurons in Behaving Caenorhabditis Elegans

article

Imaging Dendritic Spines in Caenorhabditis elegans

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved