JoVE Journal

Behavior

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The Modified Hole Board - Measuring Behavior, Cognition and Social Interaction in Mice and Rats

17.7K Views

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08:16 min

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April 8th, 2015

DOI :

10.3791/52529-v

April 8th, 2015

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Maaike Labots¹^,², Hein A. Van Lith¹^,², Frauke Ohl¹^,², Saskia S. Arndt¹^,²

¹Department of Animals in Science and Society, Utrecht University, ²Brain Center Rudolf Magnus

Summary

This protocol describes the modified hole board, which is a behavioral test set-up that comprises the characteristics of an open field and a traditional hole board. This set-up enables the differential analysis of unconditioned behavior of small laboratory mammals as well as the analysis of cognitive abilities.

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Modified Hole Board

Social Interaction

Reference Memory

Behavioral Flexibility

Adaptive Capacities

Experimental Animals

Chapters in this video

0:05

Title

1:30

Behavioral Testing - Without the Presence of Group Mates (including Novel Object Recognition)

3:11

Behavior Testing in the Presence of Group Mates

3:52

Cognitive Testing Using the Modified Hole Board

6:04

Results: Cognitive Testing Using the Modified Hole Board

7:55

Conclusion

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