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Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring

DOI :

10.3791/52757-v

June 23rd, 2015

June 23rd, 2015

11,246 Views

1Department of Internal Medicine, Division of Nephrology, Mayo Clinic, 2Department of Biochemistry and Molecular Biology, Mayo Clinic

The use of ultra-high field MRI as a non-invasive way to obtain phenotypic information of rodent models for polycystic kidney disease and to monitor interventions is described. Compared with the traditional histological approach, MRI images can be acquired in vivo, allowing for longitudinal follow-up.

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Ultra high Field MRI

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