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15.2K Views
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13:58 min
July 29th, 2015
DOI :
10.3791/52831-v
Chapters
0:05
Title
2:21
Punch Biopsy
6:12
Infection of Human Fibroblasts with Sendai Virus and Transdifferentiation
8:47
Isolation of Putative Induced Neural Progenitor Cells (iNPC) Colonies
10:15
Differentiation of iNPCs
12:04
Results: Reprogramming of Fibroblasts into Neural Precursors and their Cellular Validation
13:20
Conclusion
Summary
人工多能性幹細胞の生成は、自家移植の導出のための魅力的な展望を提供しています。しかし、多能性状態と面倒な再分化の進行はまだ臨床の翻訳を妨げます。ここでは、成人のヒト線維芽細胞の誘導および誘導神経前駆細胞への直接変換と神経系統へその後の分化を説明します。
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