JoVE Logo
Faculty Resource Center

Sign In

Extracellular Recording of Neuronal Activity Combined with Microiontophoretic Application of Neuroactive Substances in Awake Mice

DOI :

10.3791/53914-v

May 21st, 2016

May 21st, 2016

9,782 Views

1Auditory Neuroscience Laboratory, Institute of Neuroscience of Castilla y León, University of Salamanca, 2Neural Systems Laboratory, Institute for Systems Research, University of Maryland, 3Medical Research Council Institute of Hearing Research, 4Department of Cell Biology and Pathology, Faculty of Medicine, University of Salamanca

We present methods for the construction of electrodes to simultaneously record extracellular neural activity and release multiple neuroactive substances at the vicinity of the recording sites in awake mice. This technique allows the detailed analysis of putative local synaptic inputs to the neuron of interest.

Tags

Keywords Extracellular Recording

-- Views

Related Videos

article

Recording Large-scale Neuronal Ensembles with Silicon Probes in the Anesthetized Rat

article

Preparation of an Awake Mouse for Recording Neural Responses and Injecting Tracers

article

Retrograde Fluorescent Labeling Allows for Targeted Extracellular Single-unit Recording from Identified Neurons In vivo

article

Recording and Analysis of Circadian Rhythms in Running-wheel Activity in Rodents

article

A Procedure for Implanting Organized Arrays of Microwires for Single-unit Recordings in Awake, Behaving Animals

article

Utilizing Combined Methodologies to Define the Role of Plasma Membrane Delivery During Axon Branching and Neuronal Morphogenesis

article

Recording Temperature-induced Neuronal Activity through Monitoring Calcium Changes in the Olfactory Bulb of Xenopus laevis

article

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats

article

Optogenetics Identification of a Neuronal Type with a Glass Optrode in Awake Mice

article

In vivo Calcium Imaging in Mouse Inferior Olive

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved