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Preparation of an Awake Mouse for Recording Neural Responses and Injecting Tracers

DOI :

10.3791/3755-v

June 26th, 2012

June 26th, 2012

19,099 Views

1Department of Neuroscience, Johns Hopkins University, 2Garvan Institute of Medical Research, 3School of Biological Sciences, Washington State University, 4Department of Otolaryngology-HNS, Johns Hopkins University

Electrophysiological characterization of neuronal responses is important for understanding brain function and for guiding the placement of dyes for pathway tracing. However, many studies are performed in anesthetized animals. To understand brain function without anesthetics, we developed a method to record neuronal response properties and inject dyes in awake mouse.

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Awake Mouse

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