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High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)

DOI :

10.3791/53987-v

11:38 min

May 10th, 2016

May 10th, 2016

11,652 Views

1Biological System Research (BSR), Philip Morris International R&D

The objective of the study was to assess the biological impact of 15 cigarette smoke constituents using a combination of an impedance-based real time cell analyzer and a high-content screening (HCS)-based platform for toxicological assessment in vitro. This study provides information on effective doses, toxicity and modes of action of the tested compounds.

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High Content Screening Analysis

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