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Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices

DOI :

10.3791/57042-v

12:04 min

May 9th, 2018

May 9th, 2018

12,982 Views


In view of the 3Rs principle, respiratory models as alternatives to animal studies are evolving. Especially for risk assessment of respiratory substances, there is a lack of appropriate assays. Here, we describe the use of human precision-cut lung slices for the assessment of airborne substances.

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Human Precision cut Lung Slices

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