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Intravascular Delivery of Biologics to the Rat Kidney

DOI :

10.3791/54418-v

September 1st, 2016

September 1st, 2016

7,022 Views

1Divisions of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, 2Divisions of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic

The administration of drugs for recovery of kidney function requires control of the localization and distribution of the therapeutic compound. Here, we describe in detail a simple technique for intrarenal delivery of drugs in rats. This procedure may be easily performed with no mortality and high reproducibility.

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