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Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice

DOI :

10.3791/54432-v

December 1st, 2017

December 1st, 2017

14,883 Views

1Unité d’Immunobiologie des Cellules Dendritiques, Department of Immunology, Institut Pasteur, INSERM U818, 2Genentech

The established model of transurethral catheterization of mice allows the study of bladder pathologies, including urinary tract infection, but can only be performed in females. A new model of male transurethral instillation, presented here, will enable research in an area marked by strong clinical and epidemiological differences between the sexes.

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