Results: Metabolic Exchange of [1-13C]Pyruvate to [1-13C]Lactate in Prostate Carcinoma (PC3) Cells
10:40
Conclusion
Transcript
The overall goal of this procedure is to hyperpolarize carbon 13-labelled molecules using dynamic nuclear polarization, and to measure their enyzmatic conversion using carbon 13 magnetic resonance, retroscopic imaging, in vitro. This method increa
Sign in or start your free trial to access this content
Dynamic nuclear polarization with subsequent sample dissolution has enabled real-time studies of metabolism in biological systems. Hyperpolarized [1-13C]pyruvate was used to study lactate dehydrogenase activity in a prostate carcinoma cell line in vitro.