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Measuring the Spin-Lattice Relaxation Magnetic Field Dependence of Hyperpolarized [1-13C]pyruvate

DOI :

10.3791/59399-v

September 13th, 2019

September 13th, 2019

6,338 Views

1Department of Medical Biophysics, Western University, 2Imaging Research Laboratory, Robarts Research Institute, Western University, 3Ontario Institute for Cancer Research

We present a protocol to measure the magnetic field dependence of the spin-lattice relaxation time of 13C-enriched compounds, hyperpolarized by means of dynamic nuclear polarization, using fast field-cycled relaxometry. Specifically, we have demonstrated this with [1-13C]pyruvate, but the protocol could be extended to other hyperpolarized substrates.

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Hyperpolarized

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