Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity (AIDN): A Translational Neuroscience Approach

11.2K Views

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06:38 min

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June 11th, 2017

DOI :

10.3791/55193-v

June 11th, 2017

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Emmett E. Whitaker¹^,², Christopher Z. Zheng¹, Bruno Bissonnette¹^,²^,³, Andrew D. Miller⁴, Tanner L. Koppert¹^,², Joseph D. Tobias¹^,², Christopher R. Pierson⁵^,⁶, Fedias L. Christofi¹

¹Department of Anesthesiology, Ohio State University College of Medicine, ²Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, ³Department of Anaesthesia and Critical Care Medicine, University of Toronto, ⁴Department of Biomedical Sciences, Section of Anatomic Pathology, Cornell University College of Veterinary Medicine, ⁵Department of Pathology and Anatomy, Ohio State University College of Medicine, ⁶Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital

Summary

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Keywords Piglet Model

Anesthetic induced Developmental Neurotoxicity AIDN

Translational Neuroscience

Physiologic Homeostasis

End tidal Carbon Dioxide

Ophthalmic Ointment

Antibiotic

Sterile Field

Femoral Neurovascular Bundle

Chapters in this video

0:05

Title

0:45

Preparing the Animal

2:49

Femoral Artery Catheterization

4:11

Collecting Data and Completing Surgery

5:30

Results: Consistency and Reproducibility of Lab Values

6:07

Conclusion

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