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3D Magnetic Stem Cell Aggregation and Bioreactor Maturation for Cartilage Regeneration

DOI :

10.3791/55221-v

April 27th, 2017

April 27th, 2017

9,619 Views

1Laboratoire Matière et Systèmes Complexes (MSC), UMR 7057 CNRS and University Paris Diderot

Chondrogenesis from stem cells requires fine tuning the culture conditions. Here, we present a magnetic approach for condensing cells, an essential step to initiate chondrogenesis. In addition, we show that dynamic maturation in a bioreactor applies mechanical stimulation to the cellular constructs and enhances cartilaginous extracellular matrix production.

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3D Magnetic Cell Aggregation

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