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PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator

DOI :

10.3791/56601-v

December 28th, 2017

December 28th, 2017

9,238 Views

1Department of Nuclear Medicine, Ghent University Hospital, 2IBiTech-MEDISIP, Department of Electronics and Information Systems, Ghent University, 3Department of Radiation Oncology, Ghent University Hospital

In the past, small animal irradiation was usually performed without the ability to target a well-delineated tumor volume. The goal was to mimic the treatment of human glioblastoma in rats. Using a small animal irradiation platform, we performed MRI-guided 3D conformal irradiation with PET-based sub-volume boosting in a preclinical setting.

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PET

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