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Overview of Bioprocess Engineering

Overview

Bioprocessing is a method that uses living organisms to produce a desired target product. Often, bioprocessing refers to the use of bioreactors to produce protein products from genetically engineered organisms. This field is responsible for the large-scale manufacture of biotherapeutics; drugs that have become essential to improving the quality of life for many with complex diseases like cancer, autoimmune diseases and HIV/AIDS.

This video will introduce the engineering approach to designing a targeted protein-production system. The prominent methods in the field, as well as some key challenges, and applications of the technology are also considered.

Procedure

Bioprocess engineering is a field that uses many engineering disciplines to produce a specific product from living organisms. Typically, the organisms are genetically modified cells that are engineered to produce a specific product protein or chemical. The cells are then grown on the large scale in order to produce the product which is later purified using downstream processes, such as chromatography. This video will introduce an example bioprocess, review prominent methods in the field, as well as som

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Bioprocess EngineeringEngineering DisciplinesLiving OrganismsGenetically Modified CellsSpecific ProductProteinChemicalLarge ScaleDownstream ProcessesChromatographyExample BioprocessProminent MethodsKey ChallengesApplicationsTechnologyBacterial CellsFungal CellsMammalian CellsUpstream ProcessSuspension CultureVessel BioreactorCell CultureCell DensityProduct Protein HarvestingSecretionLysisPurification Process

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0:06

Overview

0:51

A Typical Bioprocess

2:52

Prominent Methods

4:48

Key Challenges

6:02

Applications

7:19

Summary

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