Optical biosensors are sensors that detect a biological target or targets of interest using light. These devices have found applications in healthcare, pharmaceuticals, environmental monitoring, Homeland Security, and even the battlefield. Optical biosensors are broadly divided into label-based and label-free sensors. An example of label-based sensing is Polymerase Chain Reaction, or PCR, that uses fluorescent labels, or fluorophores, to quantify the amplified target DNA. An example of a label-free met