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JoVE Journal

Neuroscience

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The Power of Interstimulus Interval for the Assessment of Temporal Processing in Rodents

6.8K Views

10:27 min

April 19th, 2019

April 19th, 2019

6,771 Views

0:04

Title

0:50

Creation of Experimental Programs

5:25

Protocol Structure

6:20

Results: Cross-Sectional Assessment of Temporal Processing

9:44

Conclusion

Transcript

This method can help answer key questions in the field of neuroscience by characterizing neurocognitive disorders and their progression across the lifespan via cross-sectional and longitudinal assessments. The main advantage of this technique is t

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Temporal processing, a preattentive process, may underlie deficits in higher-level cognitive processes, including attention, commonly observed in neurocognitive disorders. Using prepulse inhibition as an exemplar paradigm, we present a protocol for manipulating interstimulus interval (ISI) to establish the shape of the ISI function to provide an assessment of temporal processing.

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