Surgical Robot Hardware Setup and Software Preparation
2:00
Surgery and Skull Preparation
3:17
Evans Blue Tail Vein Injection
3:57
Surgical Robot Drilling Procedure
6:33
Thermocouple Evaluation
7:31
Results: Semi-Automated Bone Drilling of Cranial Windows to Mitigate Thermal Blood-Brain Barrier Damage
9:00
Conclusion
Transcript
This protocol provides a method for evaluating vascular damage as a result of cranial window drilling. A surgical robot offers improved consistencies across procedures while reducing the amount of training to learn the technique. During this proce
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Cranial windows have become a ubiquitously implemented surgical technique to allow for intravital imaging in transgenic mice. This protocol describes the use of a surgical robot that performs semi-automated bone drilling of cranial windows and can help reduce surgeon-to-surgeon variability and partially mitigate thermal blood-brain barrier damage.