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Assessment of Thermal Damage from Robot-Drilled Craniotomy for Cranial Window Surgery in Mice

DOI :

10.3791/64188-v

November 11th, 2022

November 11th, 2022

1,661 Views

1Department of Biomedical Engineering, Case Western Reserve University, 2Advanced Platform Technology Center, Louis Stokes Cleveland VA Medical Center

Cranial windows have become a ubiquitously implemented surgical technique to allow for intravital imaging in transgenic mice. This protocol describes the use of a surgical robot that performs semi-automated bone drilling of cranial windows and can help reduce surgeon-to-surgeon variability and partially mitigate thermal blood-brain barrier damage.

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Thermal Damage

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