Department of Microbiology,
Medical School,
Department of Microbiology, Medical School
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CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract.
The Journal of experimental medicine Sep, 2004 | Pubmed ID: 15365096
Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.
Nature Apr, 2005 | Pubmed ID: 15793562
Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus.
Journal of virology Jul, 2005 | Pubmed ID: 15994816
Potential roles of follicular dendritic cell-associated osteopontin in lymphoid follicle pathology and repair and in B cell regulation in HIV-1 and SIV infection.
The Journal of infectious diseases Oct, 2005 | Pubmed ID: 16136472
Perils at mucosal front lines for HIV and SIV and their hosts.
Nature reviews. Immunology Oct, 2005 | Pubmed ID: 16200081
Amount of lymphatic tissue fibrosis in HIV infection predicts magnitude of HAART-associated change in peripheral CD4 cell count.
AIDS (London, England) Dec, 2005 | Pubmed ID: 16284469
Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection.
The Journal of infectious diseases Mar, 2006 | Pubmed ID: 16453267
Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection.
Clinical and vaccine immunology : CVI May, 2006 | Pubmed ID: 16682476
Gene expression alterations in brains of mice infected with three strains of scrapie.
BMC genomics , 2006 | Pubmed ID: 16700923
Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.
Nature medicine Nov, 2006 | Pubmed ID: 17057712
Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection.
The Journal of infectious diseases Feb, 2007 | Pubmed ID: 17230415
Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1.
The Journal of experimental medicine Apr, 2007 | Pubmed ID: 17389241
Introduction from the Co-Chairmen of the US and Japanese delegation of the US-Japan Cooperative Medical Science Program.
Tuberculosis (Edinburgh, Scotland) Aug, 2007 | Pubmed ID: 17646134
Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice.
PLoS medicine Jan, 2008 | Pubmed ID: 18198941
Simian immunodeficiency virus-induced intestinal cell apoptosis is the underlying mechanism of the regenerative enteropathy of early infection.
The Journal of infectious diseases Feb, 2008 | Pubmed ID: 18199035
Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis.
Journal of virology Apr, 2008 | Pubmed ID: 18216113
Genital ulcers facilitate rapid viral entry and dissemination following intravaginal inoculation with cell-associated simian immunodeficiency virus SIVmac239.
Journal of virology Apr, 2008 | Pubmed ID: 18272571
In situ staining using MHC class I tetramers.
Current protocols in immunology / edited by John E. Coligan ... [et al.] Jan, 2005 | Pubmed ID: 18432944
Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques.
Journal of immunology (Baltimore, Md. : 1950) May, 2008 | Pubmed ID: 18453600
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.
The Journal of clinical investigation Jun, 2008 | Pubmed ID: 18497876
The role of collagen deposition in depleting CD4+ T cells and limiting reconstitution in HIV-1 and SIV infections through damage to the secondary lymphoid organ niche.
Seminars in immunology Jun, 2008 | Pubmed ID: 18595731
Collagen deposition limits immune reconstitution in the gut.
The Journal of infectious diseases Aug, 2008 | Pubmed ID: 18598193
Glycerol monolaurate does not alter rhesus macaque (Macaca mulatta) vaginal lactobacilli and is safe for chronic use.
Antimicrobial agents and chemotherapy Dec, 2008 | Pubmed ID: 18838587
Glycerol monolaurate prevents mucosal SIV transmission.
Nature Apr, 2009 | Pubmed ID: 19262509
Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection.
Science (New York, N.Y.) Mar, 2009 | Pubmed ID: 19325114
Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses.
Journal of virology Jun, 2009 | Pubmed ID: 19369333
Microarray analysis of lymphatic tissue reveals stage-specific, gene expression signatures in HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) Aug, 2009 | Pubmed ID: 19596987
Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys.
The Journal of clinical investigation Dec, 2009 | Pubmed ID: 19959874
Targeting early infection to prevent HIV-1 mucosal transmission.
Nature Mar, 2010 | Pubmed ID: 20220840
AIDS and optic neuritis in a rhesus monkey infected with the R5 clade C SHIV-1157ipd3N4.
Journal of medical primatology Oct, 2010 | Pubmed ID: 20412378
A role for syndecan-1 and claudin-2 in microbial translocation during HIV-1 infection.
Journal of acquired immune deficiency syndromes (1999) Nov, 2010 | Pubmed ID: 20700059
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.
PLoS pathogens , 2010 | Pubmed ID: 20808901
Host genes associated with HIV-1 replication in lymphatic tissue.
Journal of immunology (Baltimore, Md. : 1950) Nov, 2010 | Pubmed ID: 20935203
Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy.
The Journal of infectious diseases Nov, 2010 | Pubmed ID: 20939732
Early events in sexual transmission of HIV and SIV and opportunities for interventions.
Annual review of medicine Feb, 2011 | Pubmed ID: 21054171
Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections.
The Journal of clinical investigation Mar, 2011 | Pubmed ID: 21393864
The immunosuppressive role of IL-32 in lymphatic tissue during HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2011 | Pubmed ID: 21525393
Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.
PLoS pathogens Jan, 2012 | Pubmed ID: 22241988
In situ tetramer staining.
Journal of immunological methods Oct, 2002 | Pubmed ID: 12213340
Persistent abnormalities in lymphoid tissues of human immunodeficiency virus-infected patients successfully treated with highly active antiretroviral therapy.
The Journal of infectious diseases Oct, 2002 | Pubmed ID: 12355359
Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis.
The Journal of clinical investigation Oct, 2002 | Pubmed ID: 12393849
Transmission, acute HIV-1 infection and the quest for strategies to prevent infection.
Nature medicine Jul, 2003 | Pubmed ID: 12835704
Functional genomic analysis of the response of HIV-1-infected lymphatic tissue to antiretroviral therapy.
The Journal of infectious diseases Feb, 2004 | Pubmed ID: 14767808
Roles of substrate availability and infection of resting and activated CD4+ T cells in transmission and acute simian immunodeficiency virus infection.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2004 | Pubmed ID: 15064398
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