Ashley T. Haase

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract.

Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus.

Potential roles of follicular dendritic cell-associated osteopontin in lymphoid follicle pathology and repair and in B cell regulation in HIV-1 and SIV infection.

Perils at mucosal front lines for HIV and SIV and their hosts.

Amount of lymphatic tissue fibrosis in HIV infection predicts magnitude of HAART-associated change in peripheral CD4 cell count.

Premature induction of an immunosuppressive regulatory T cell response during acute simian immunodeficiency virus infection.

Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4+ T cells in human immunodeficiency virus type 1 infection.

Gene expression alterations in brains of mice infected with three strains of scrapie.

Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.

Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection.

Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1.

Introduction from the Co-Chairmen of the US and Japanese delegation of the US-Japan Cooperative Medical Science Program.

Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice.

Simian immunodeficiency virus-induced intestinal cell apoptosis is the underlying mechanism of the regenerative enteropathy of early infection.

Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis.

Genital ulcers facilitate rapid viral entry and dissemination following intravaginal inoculation with cell-associated simian immunodeficiency virus SIVmac239.

In situ staining using MHC class I tetramers.

Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques.

Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.

The role of collagen deposition in depleting CD4+ T cells and limiting reconstitution in HIV-1 and SIV infections through damage to the secondary lymphoid organ niche.

Collagen deposition limits immune reconstitution in the gut.

Glycerol monolaurate does not alter rhesus macaque (Macaca mulatta) vaginal lactobacilli and is safe for chronic use.

Glycerol monolaurate prevents mucosal SIV transmission.

Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection.

Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses.

Microarray analysis of lymphatic tissue reveals stage-specific, gene expression signatures in HIV-1 infection.

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys.

Targeting early infection to prevent HIV-1 mucosal transmission.

AIDS and optic neuritis in a rhesus monkey infected with the R5 clade C SHIV-1157ipd3N4.

A role for syndecan-1 and claudin-2 in microbial translocation during HIV-1 infection.

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.

Host genes associated with HIV-1 replication in lymphatic tissue.

Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapy.

Early events in sexual transmission of HIV and SIV and opportunities for interventions.

Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections.

The immunosuppressive role of IL-32 in lymphatic tissue during HIV-1 infection.

Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.

In situ tetramer staining.

Persistent abnormalities in lymphoid tissues of human immunodeficiency virus-infected patients successfully treated with highly active antiretroviral therapy.

Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis.

Transmission, acute HIV-1 infection and the quest for strategies to prevent infection.

Functional genomic analysis of the response of HIV-1-infected lymphatic tissue to antiretroviral therapy.

Roles of substrate availability and infection of resting and activated CD4+ T cells in transmission and acute simian immunodeficiency virus infection.