Department of Biomedical Engineering,
Department of Cell & Developmental Biology,
Division of Hematology & Medical Oncology,
Knight Cancer Institute,
Department of Cell & Developmental Biology, Division of Hematology & Medical Oncology, Knight Cancer Institute
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Comparative efficacy between the glycoprotein IIb/IIIa antagonists roxifiban and orbofiban in inhibiting platelet responses in flow models of thrombosis.
Journal of cardiovascular pharmacology Apr, 2002 | Pubmed ID: 11904529
Fluid shear regulates the kinetics and molecular mechanisms of activation-dependent platelet binding to colon carcinoma cells.
Biophysical journal Aug, 2002 | Pubmed ID: 12124268
Exogenous eosinophil activation converts PSGL-1-dependent binding to CD18-dependent stable adhesion to platelets in shear flow.
American journal of physiology. Cell physiology May, 2003 | Pubmed ID: 12529243
Evaluation of platelet antagonists in in vitro flow models of thrombosis.
Methods in molecular medicine , 2004 | Pubmed ID: 14733325
Preferential binding of platelets to monocytes over neutrophils under flow.
Biochemical and biophysical research communications Apr, 2005 | Pubmed ID: 15721313
Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow.
The Journal of biological chemistry Nov, 2005 | Pubmed ID: 16195235
Laminin stimulates spreading of platelets through integrin alpha6beta1-dependent activation of GPVI.
Blood Feb, 2006 | Pubmed ID: 16219796
Distinct but critical roles for integrin alphaIIbbeta3 in platelet lamellipodia formation on fibrinogen, collagen-related peptide and thrombin.
The FEBS journal Nov, 2006 | Pubmed ID: 17032352
Vav family proteins are required for optimal regulation of PLCgamma2 by integrin alphaIIbbeta3.
The Biochemical journal Feb, 2007 | Pubmed ID: 17054426
GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk.
Arteriosclerosis, thrombosis, and vascular biology Feb, 2007 | Pubmed ID: 17110603
Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates.
Blood May, 2007 | Pubmed ID: 17227834
Minimal regulation of platelet activity by PECAM-1.
Platelets Feb, 2007 | Pubmed ID: 17365855
The leech product saratin is a potent inhibitor of platelet integrin alpha2beta1 and von Willebrand factor binding to collagen.
The FEBS journal Mar, 2007 | Pubmed ID: 17489103
Thrombin mutant W215A/E217A acts as a platelet GPIb antagonist.
Arteriosclerosis, thrombosis, and vascular biology Feb, 2008 | Pubmed ID: 17962622
Capture of flowing endothelial cells using surface-immobilized anti-kinase insert domain receptor antibody.
Tissue engineering. Part C, Methods Jun, 2008 | Pubmed ID: 18544026
Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI.
Blood Jan, 2009 | Pubmed ID: 18945968
Distinct extracellular matrix microenvironments of progenitor and carotid endothelial cells.
Journal of biomedical materials research. Part A Nov, 2009 | Pubmed ID: 18985765
Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2009 | Pubmed ID: 19116273
Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2009 | Pubmed ID: 19141632
Single particle quantum dot imaging achieves ultrasensitive detection capabilities for Western immunoblot analysis.
ACS nano Jun, 2009 | Pubmed ID: 19453141
Identification of coagulation factor XI as a ligand for platelet apolipoprotein E receptor 2 (ApoER2).
Arteriosclerosis, thrombosis, and vascular biology Oct, 2009 | Pubmed ID: 19661487
Effect of sex difference on platelet adhesion, spreading and aggregate formation under flow.
Thrombosis and haemostasis Nov, 2009 | Pubmed ID: 19888535
Cytoskeletal structure regulates endothelial cell immunogenicity independent of fluid shear stress.
American journal of physiology. Cell physiology Feb, 2010 | Pubmed ID: 19923423
Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear.
PloS one , 2010 | Pubmed ID: 20454680
Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis.
Journal of neuroimmunology Aug, 2010 | Pubmed ID: 20546940
Safety and antithrombotic efficacy of moderate platelet count reduction by thrombopoietin inhibition in primates.
Science translational medicine Jun, 2010 | Pubmed ID: 20574069
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo.
Blood Nov, 2010 | Pubmed ID: 20634381
Molecular imaging of activated von Willebrand factor to detect high-risk atherosclerotic phenotype.
JACC. Cardiovascular imaging Sep, 2010 | Pubmed ID: 20846630
Breakup feared after filamin leaves GPIb.
Blood Mar, 2011 | Pubmed ID: 21372161
Thrombin mutant W215A/E217A treatment improves neurological outcome and reduces cerebral infarct size in a mouse model of ischemic stroke.
Stroke; a journal of cerebral circulation Jun, 2011 | Pubmed ID: 21512172
S6K1 and mTOR regulate Rac1-driven platelet activation and aggregation.
Blood Sep, 2011 | Pubmed ID: 21757621
Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes.
Journal of leukocyte biology Nov, 2011 | Pubmed ID: 21807745
Platelet shape change and spreading.
Methods in molecular biology (Clifton, N.J.) , 2012 | Pubmed ID: 22130702
Optical detection of indocyanine green encapsulated biocompatible poly (lactic-co-glycolic) acid nanoparticles with photothermal optical coherence tomography.
Optics letters Mar, 2012 | Pubmed ID: 22378459
Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis.
Blood May, 2012 | Pubmed ID: 22442348
Regulation of the mTOR-Rac1 axis in platelet function.
Small GTPases Jan-Mar, 2012 | Pubmed ID: 22714420
Optical quantification of cellular mass, volume, and density of circulating tumor cells identified in an ovarian cancer patient.
Frontiers in oncology , 2012 | Pubmed ID: 22826822
Hyaluronan anchored to activated CD44 on central nervous system vascular endothelial cells promotes lymphocyte extravasation in experimental autoimmune encephalomyelitis.
The Journal of biological chemistry Sep, 2012 | Pubmed ID: 22865853
Quantification of cellular volume and sub-cellular density fluctuations: comparison of normal peripheral blood cells and circulating tumor cells identified in a breast cancer patient.
Frontiers in oncology , 2012 | Pubmed ID: 22934287
Development of coagulation factor probes for the identification of procoagulant circulating tumor cells.
Frontiers in oncology , 2012 | Pubmed ID: 22973554
Do circulating tumor cells play a role in coagulation and thrombosis?
Frontiers in oncology , 2012 | Pubmed ID: 22973557
Measurement of single cell refractive index, dry mass, volume, and density using a transillumination microscope.
Physical review letters Sep, 2012 | Pubmed ID: 23005682
Modeling and simulation of procoagulant circulating tumor cells in flow.
Frontiers in oncology , 2012 | Pubmed ID: 23050240
Exogenous modification of platelet membranes with the omega-3 fatty acids EPA and DHA reduces platelet procoagulant activity and thrombus formation.
American journal of physiology. Cell physiology Feb, 2013 | Pubmed ID: 23174566
Molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis effects of antioxidant therapy with NADPH oxidase inhibition.
Circulation. Cardiovascular imaging Jan, 2013 | Pubmed ID: 23239832
Gammaherpesvirus latency induces antibody-associated thrombocytopenia in mice.
Journal of autoimmunity May, 2013 | Pubmed ID: 23245703
Hyaluronan oligosaccharides perturb lymphocyte slow rolling on brain vascular endothelial cells: implications for inflammatory demyelinating disease.
Matrix biology : journal of the International Society for Matrix Biology Apr, 2013 | Pubmed ID: 23333375
Quantification of volume, mass, and density of thrombus formation using brightfield and differential interference contrast microscopy.
Journal of biomedical optics Jan, 2013 | Pubmed ID: 23348747
Physiological levels of blood coagulation factors IX and X control coagulation kinetics in an in vitro model of circulating tissue factor.
Physical biology Jun, 2013 | Pubmed ID: 23585459
Development of a Label-free Imaging Technique for the Quantification of Thrombus Formation.
Cellular and molecular bioengineering Dec, 2012 | Pubmed ID: 23585817
A physical sciences network characterization of non-tumorigenic and metastatic cells.
Scientific reports , 2013 | Pubmed ID: 23618955
Inhibition of Factor XII-Mediated Activation of Factor XI Provides Protection Against Experimental Acute Ischemic Stroke in Mice.
Translational stroke research Sep, 2012 | Pubmed ID: 23634198
p21 activated kinase signaling coordinates glycoprotein receptor VI-mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear.
Arteriosclerosis, thrombosis, and vascular biology Jul, 2013 | Pubmed ID: 23640496
Microfluidics and coagulation biology.
Annual review of biomedical engineering , 2013 | Pubmed ID: 23642241
Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy.
American journal of physiology. Cell physiology Aug, 2013 | Pubmed ID: 23720022
The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation.
American journal of physiology. Cell physiology Sep, 2013 | Pubmed ID: 23784547
Role of coagulation in the recruitment of colon adenocarcinoma cells to thrombus under shear.
American journal of physiology. Cell physiology Nov, 2013 | Pubmed ID: 23903698
p21-Activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophils.
PloS one , 2013 | Pubmed ID: 24019894
Histone deacetylase 6-mediated deacetylation of α-tubulin coordinates cytoskeletal and signaling events during platelet activation.
American journal of physiology. Cell physiology Dec, 2013 | Pubmed ID: 24025866
A theme series on physical biology in cancer in AJP-Cell.
American journal of physiology. Cell physiology Jan, 2014 | Pubmed ID: 24067917
Phosphatidylserine index as a marker of the procoagulant phenotype of acute myelogenous leukemia cells.
Physical biology Oct, 2013 | Pubmed ID: 24104188
Physical biology in cancer. 2. The physical biology of circulating tumor cells.
American journal of physiology. Cell physiology Jan, 2014 | Pubmed ID: 24133063
Rac and Cdc42 team up for platelets.
Blood Oct, 2013 | Pubmed ID: 24178962
Factor XII inhibition reduces thrombus formation in a primate thrombosis model.
Blood Mar, 2014 | Pubmed ID: 24408325
Network signatures of nuclear and cytoplasmic density alterations in a model of pre and postmetastatic colorectal cancer.
Journal of biomedical optics Jan, 2014 | Pubmed ID: 24441943
Measurement science in the circulatory system.
Cellular and molecular bioengineering Mar, 2014 | Pubmed ID: 24563678
1Department of Biomedical Engineering, Oregon Health & Science University, School of Medicine,
2Department of Dermatology, Oregon Health & Science University, School of Medicine,
3Department of Cell & Developmental Biology, Division of Hematology & Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, School of Medicine
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