a-method-to-study-impact-chemically-induced-ovarian-failure-on

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

The risk of cardiovascular disease (CVD) increases in post-menopausal women, yet, the role of exercise, as a preventative measure for CVD risk in ...

tubal-cytology-fallopian-tube-as-promising-tool-for-ovarian-cancer

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection

Currently, it is widely accepted that the vast majority of ovarian high-grade serous carcinoma (HGSC) originate from the fallopian tube. However, due to ...

live-cell-imaging-tgf-smad3-signaling-pathway-vitro-vivo-using-an

Live Cell Imaging of the TGF-	&beta;/Smad3 Signaling Pathway <em>In Vitro</em> and <em>In Vivo</em> Using an Adenovirus Reporter System

Transforming Growth Factor &#946; (TGF-&#946;) signaling regulates many important functions required for cellular homeostasis and is commonly found ...

dynamic-changes-lung-function-blood-flow-during-lung-adenocarcinoma

Dynamic Changes in Lung Function and Blood Flow During Lung Adenocarcinoma Progression in Mice by Whole-body Plethysmography and Doppler Ultrasound

Lung adenocarcinoma (LUAD) is a common malignant pulmonary tumor, and its progression leads to alterations in ventilation and blood flow, highlighting the ...

University of Arizona

University of Arizona College of Medicine

University of Melbourne

Chengdu University of TCM

Although closed reductions of nasal fractures and zygomatic arch fractures are considered minor procedures, improper reductions are not uncommon. Objectively evaluating reduction adequacy with imaging assistance during surgery is crucial. The authors used mobile Fluoroscan intraoperatively to assess the adequacy of closed reduction for nasal fractures and zygomatic arch fractures.

Optimizing closed reduction of nasal and zygomatic arch fractures with a mobile fluoroscan.

Acupuncture is considered to be an effective and safe treatment for obese and overweight patients, although high-quality evidence regarding the effects of acupuncture on obesity are not conclusive. The aim of the current study is to investigate the effectiveness of electro-acupuncture plus lifestyle modification for treating obese and overweight patients, in comparison with lifestyle modification alone in China.

Comparative effectiveness of electro-acupuncture plus lifestyle modification treatment for patients with simple obesity and overweight: study protocol for a randomized controlled trial.

The Shack-Hartmann wavefront sensor (SHWFS) is widely utilized for ocular aberration measurement. However, large ocular aberrations caused by individual differences can easily make the spot move out of the range of the corresponding sub-aperture in SHWFS, rendering the traditional centroiding method ineffective. This study applied a novel convolutional neural network (CNN) model to wavefront sensing for large dynamic ocular aberration measurement. The simulation results demonstrate that, compared to the modal method, the dynamic range of our method for main low-order aberrations in ocular system is increased by 1.86 to 43.88 times in variety. Meanwhile, the proposed method also has the best measurement accuracy, and the statistical root mean square (RMS) of the residual wavefronts is 0.0082 ± 0.0185 λ (mean ± standard deviation). The proposed method generally has a higher accuracy while having a similar or even better dynamic range as compared to traditional large-dynamic schemes. On the other hand, compared with recently developed deep learning methods, the proposed method has a much larger dynamic range and better measurement accuracy.

Large-Dynamic-Range Ocular Aberration Measurement Based on Deep Learning with a Shack-Hartmann Wavefront Sensor.

Shack-Hartmann-based wavefront sensing combined with deep learning, due to its fast, accurate, and large dynamic range, has been widely studied in many fields including ocular aberration measurement. Problems such as noise and corneal reflection affect the accuracy of detection in practical measuring ocular aberration systems. This paper establishes a framework comprising of a noise-added model, Hartmannograms with corneal reflections and the corneal reflection elimination algorithm. Therefore, a more realistic data set is obtained, enabling the convolutional neural network to learn more comprehensive features and carry out real machine verification. The results show that the proposed method has excellent measurement accuracy. The root mean square error (RMSE) of the residual wavefront is 0.00924 ± 0.0207 (mean ± standard deviation) in simulation and 0.0496 ± 0.0156 in a real machine. Compared with other methods, this network combined with the proposed corneal reflection elimination algorithm is more accurate, speedier, and more widely applicable in the noise and corneal reflection situations, making it a promising tool for ocular aberration measurement.

Measurement of ocular aberration in noise based on deep learning with a Shack-Hartmann wavefront sensor.

The measurement of the double-pass (DP) point spread function (PSF) provides an objective, non-invasive method for estimating intraocular scatter in the human eye. In this paper, we propose a compact double-pass objective intraocular scatter measurement system that eliminates the influence of aberrations. The system includes a far-field DP PSF detection channel and a Shack-Hartmann wavefront aberration detection channel, which are used to obtain the far-field DP PSF image and 7 orders Zernike aberration coefficients, respectively. The far-field DP PSF image is used to calculate the initial objective scatter index of the human eye. The aberration coefficients are used to reconstruct the DP PSF image caused by aberrations and calculate the influence coefficient of aberrations on intraocular scatter. By subtracting this influence coefficient from the initial objective scatter index (OSI0), the effect of aberrations on scatter measurement can be eliminated, resulting in an accurate objective scatter coefficient. Experimental verification showed that when the exit pupil aperture of this system was set to 4 mm and 6 mm, the measurement accuracy increased by at least 11.9% and 28.9%, respectively, compared to before eliminating the influence of aberrations. While improving the measurement accuracy, the system also keeps the device size and manufacturing costs at a low level, making it more suitable for clinical applications.

Compact and aberration effects-shielded objective intraocular scatter measurement system.

Based on optical coherence tomography angiography (OCTA), we investigate the effects of posterior scleral reinforcement surgery on the fundus structure and function in patients with high myopia.

ArticleTotal : 4	Year
Publication title	2014
Publication title	2017
Publication title	2018
Publication title	2025

Article	Year
Optimizing closed reduction of nasal and zygomatic arch fractures with a mobile fluoroscan. Plastic and reconstructive surgery\| PubMed ID: 20679837	2010
Comparative effectiveness of electro-acupuncture plus lifestyle modification treatment for patients with simple obesity and overweight: study protocol for a randomized controlled trial. Trials\| PubMed ID: 26576673	2015
Large-Dynamic-Range Ocular Aberration Measurement Based on Deep Learning with a Shack-Hartmann Wavefront Sensor. Sensors (Basel, Switzerland)\| PubMed ID: 38732834	2024
Measurement of ocular aberration in noise based on deep learning with a Shack-Hartmann wavefront sensor. Biomedical optics express\| PubMed ID: 39553873	2024
Compact and aberration effects-shielded objective intraocular scatter measurement system. Biomedical optics express\| PubMed ID: 39958848	2025
Optical coherence tomography angiography study on retinochoroidal thickness and blood flow changes after posterior scleral reinforcement surgery. Photodiagnosis and photodynamic therapy\| PubMed ID: 40345470	2025

Hao Chen

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