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Laboratory of Molecular Gerontology
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Giant cystic lymphangioma of the middle mediastinum.
The Indian journal of chest diseases & allied sciences Apr-Jun, 2003 | Pubmed ID: 12715936
Molecular cloning and biochemical characterization of a 3'(2'),5'-bisphosphate nucleotidase from Debaryomyces hansenii.
Yeast (Chichester, England) Apr, 2005 | Pubmed ID: 15849794
Debaryomyces hansenii, a highly osmo-tolerant and halo-tolerant yeast, maintains activated Dhog1p in the cytoplasm during its growth under severe osmotic stress.
Current genetics Sep, 2005 | Pubmed ID: 16091960
Role of N-terminal hydrophobic region in modulating the subcellular localization and enzyme activity of the bisphosphate nucleotidase from Debaryomyces hansenii.
Eukaryotic cell Feb, 2006 | Pubmed ID: 16467467
Creation of salt-insensitive 3'(2'),5'-bisphosphate nucleotidase by modeling and mutagenesis approach.
Archives of biochemistry and biophysics Jan, 2008 | Pubmed ID: 17983588
Hitting the bull's eye: novel directed cancer therapy through helicase-targeted synthetic lethality.
Journal of cellular biochemistry Apr, 2009 | Pubmed ID: 19173305
Premature aging syndrome gene WRN genetically interacts with a topoisomerase.
Cell cycle (Georgetown, Tex.) Jul, 2009 | Pubmed ID: 19587535
WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3.
Aging Feb, 2009 | Pubmed ID: 20157511
Molecular analyses of DNA helicases involved in the replicational stress response.
Methods (San Diego, Calif.) Jul, 2010 | Pubmed ID: 20188837
Delineation of WRN helicase function with EXO1 in the replicational stress response.
DNA repair Jul, 2010 | Pubmed ID: 20447876
Genetic mutants illuminate the roles of RecQ helicases in recombinational repair or response to replicational stress.
Cell cycle (Georgetown, Tex.) Aug, 2010 | Pubmed ID: 20703073
Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2011 | Pubmed ID: 21220316
National Institute on Aging, NIH
Monika Aggarwal1,
Robert M. Brosh Jr.1
1Laboratory of Molecular Gerontology, National Institute on Aging, NIH
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