Kevin Ryan

Requirements of the RNA polymerase II C-terminal domain for reconstituting pre-mRNA 3' cleavage.

Differences in health care quality for children and adults under managed care: justification for separate quality assessments?

Cancer: pinning a change on p53.

Health plan quality-of-care information is undermined by voluntary reporting.

p53 activates ICAM-1 (CD54) expression in an NF-kappaB-independent manner.

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.

Testing of the additivity-based protein sequence to reactivity algorithm.

Three dimensional architectures of ultra-high density semiconducting nanowires deposited on chip.

Quality of care for children in commercial and Medicaid managed care.

The synthesis of matrices of embedded semiconducting nanowires.

Improving health with tobacco dollars from the MSA: the Arkansas experience.

Evidence that polyadenylation factor CPSF-73 is the mRNA 3' processing endonuclease.

Arkansas Tobacco Settlement Proceeds Act of 2000: results from education and engagement with policy makers and the public.

Loss of nuclear factor-kappaB is tumor promoting but does not substitute for loss of p53.

Mechanistic and predictive profiling of 5-Fluorouracil resistance in human cancer cells.

Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylation.

Splicing DNA-damage responses to tumour cell death.

Intracellular signalling and cancer: complex pathways lead to multiple targets.

Executive summary of the AVMA-Pfizer business practices study.

Public health and the politics of school immunization requirements.

Identification and characterization of small molecule modulators of KChIP/Kv4 function.

An open-label trial of levetiracetam for treatment of cervical dystonia.

End of day dyskinesia in advanced Parkinson's disease can be eliminated by bilateral subthalamic nucleus or globus pallidus deep brain stimulation.

Severe occupational injuries among older workers: demographic factors, time of injury, place and mechanism of injury, length of stay, and cost data.

Electric-field-assisted assembly of perpendicularly oriented nanorod superlattices.

Arkansas fights fat: translating research into policy to combat childhood and adolescent obesity.

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.

DRAM links autophagy to p53 and programmed cell death.

Impact of addition of philosophical exemptions on childhood immunization rates.

A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo.

Public health "malpractice" and the obesity epidemic.

Pre-mRNA 3' cleavage is reversibly inhibited in vitro by cleavage factor dephosphorylation.

Self-assembly of vertically aligned nanorod supercrystals using highly oriented pyrolytic graphite.

Targeting the p53 family for cancer therapy: 'big brother' joins the fight.

Hzf and hCAS/CSE1L: making the right choice in p53-mediated tumour suppression.

Lessons learned while implementing a legislated school policy: body mass index assessments among Arkansas's public school students.

Legal duty to protect the public.

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.

Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis.

Inhibition of stearoyl CoA desaturase activity induces hypercholesterolemia in the cholesterol-fed hamster.

Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapy.

Finishing touches: post-translational modification of protein factors involved in mammalian pre-mRNA 3' end formation.

Am I my brother's keeper? A proposal to determine state governments' affirmative duty to advance public health.

iASPP inhibition: increased options in targeting the p53 family for cancer therapy.

Targeted online liquid chromatography electron capture dissociation mass spectrometry for the localization of sites of in vivo phosphorylation in human Sprouty2.

Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation.

Effect of dietary conjugated linoleic acid isomers on lipid metabolism in hamsters fed high-carbohydrate and high-fat diets.

Changes in protein profiles during course of experimental glomerulonephritis.

The importance of odorant conformation to the binding and activation of a representative olfactory receptor.

Small molecule activators of pre-mRNA 3' cleavage.

Arkansas Act 1220 of 2003 to reduce childhood obesity: its implementation and impact on child and adolescent body mass index.

Angiotensin I is largely converted to angiotensin (1-7) and angiotensin (2-10) by isolated rat glomeruli.

Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants and kinetic studies with aminopyridine and triazolopyrazine inhibitors.

Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity.

Characterizing the effects of the juxtamembrane domain on vascular endothelial growth factor receptor-2 enzymatic activity, autophosphorylation, and inhibition by axitinib.

The evolution of pseudo-spherical silicon nanocrystals to tetrahedra, mediated by phosphonic acid surfactants.

Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy.

Spontaneous room temperature elongation of CdS and Ag2S nanorods via oriented attachment.

c-Jun NH2-terminal kinase activation is essential for DRAM-dependent induction of autophagy and apoptosis in 2-methoxyestradiol-treated Ewing sarcoma cells.

Surveillance, screening, and reporting children's BMI in a school-based setting: a legal perspective.

Growth factor signaling permits hypoxia-induced autophagy by a HIF1alpha-dependent, BNIP3/3L-independent transcriptional program in human cancer cells.

p53 and metabolism.

Block copolymer mediated stabilization of sub-5 nm superparamagnetic nickel nanoparticles in an aqueous medium.

Centimetre scale assembly of vertically aligned and close packed semiconductor nanorods from solution.

Evidence for the interplay between JNK and p53-DRAM signalling pathways in the regulation of autophagy.

The role of autophagy in tumour development and cancer therapy.

Structure of HIV-1 reverse transcriptase with the inhibitor beta-Thujaplicinol bound at the RNase H active site.

Autophagy: an adaptable modifier of tumourigenesis.

p53-mediated induction of Noxa and p53AIP1 requires NFkappaB.

Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B.

Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1.

Discrimination of saturated aldehydes by the rat I7 olfactory receptor.

A multi-rate kinetic model for spontaneous oriented attachment of CdS nanorods.

Directing semiconductor nanorod assembly into 1D or 2D supercrystals by altering the surface charge.

Cancer: Viruses' backup plan.

Rolling Circle DNA Synthesis: Small Circular Oligonucleotides as Efficient Templates for DNA Polymerases.

Protein restriction in the pregnant mouse modifies fetal growth and pulmonary development: role of fetal exposure to {beta}-hydroxybutyrate.

p53 and senescence: A little goes a long way.

p53 and senescence: a little goes a long way.

p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival.

p53 and autophagy in cancer: guardian of the genome meets guardian of the proteome.

Protein immobilisation on perpendicularly aligned gold tipped nanorod assemblies.

The multiple roles of autophagy in cancer.

Perpendicular growth of catalyst-free germanium nanowire arrays.

Circular single-stranded synthetic DNA delivery vectors for microRNA.

Comparing a single case to a control sample: testing for neuropsychological deficits and dissociations in the presence of covariates.

Complete synthesis of germanium nanocrystal encrusted carbon colloids in supercritical CO2 and their superhydrophobic properties.

The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy.

Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).

Public policy versus individual rights in childhood obesity interventions: perspectives from the Arkansas experience with Act 1220 of 2003.

MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity.

Electrophoretic deposition of poly(3-decylthiophene) onto gold-mounted cadmium selenide nanorods.

A facile spin-cast route for cation exchange of multilayer perpendicularly-aligned nanorod assemblies.

Elevated plasma factor VIII levels in patients with venous thrombosis--constitutional risk factor or secondary epiphenomenon?

DRAM-1 encodes multiple isoforms that regulate autophagy.

p53 and tumor surveillance: killer finds way to recruit assassins.

Autophagy and cancer.

Tumor regression following intravenous administration of a tumor-targeted p73 gene delivery system.

Colloidal synthesis of wurtzite Cu2ZnSnS4 nanorods and their perpendicular assembly.

Gilt Groupe's CEO on building a team of A players.

Insight into the 3D architecture and quasicrystal symmetry of multilayer nanorod assemblies from Moiré interference patterns.

Size controlled growth of germanium nanorods and nanowires by solution pyrolysis directly on a substrate.

The Effects of Prenatal Protein Restriction on β-Adrenergic Signalling of the Adult Rat Heart during Ischaemia Reperfusion.

Analysis of macroautophagy by immunohistochemistry.

Inhibition of autophagy impairs tumor cell invasion in an organotypic model.

Vaccine policy and Arkansas childhood immunization exemptions: a multi-year review.

Autophagy and cancer--issues we need to digest.

Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens.

Do mountain pine beetle outbreaks change the probability of active crown fire in lodgepole pine forests? Comment.

Assembly of CuIn(1-x)Ga(x)S2 nanorods into highly ordered 2D and 3D superstructures.

Does androgen-ablation therapy (AAT) associated autophagy have a pro-survival effect in LNCaP human prostate cancer cells?

Discovery of a Novel Class of Exquisitely Selective Mesenchymal-Epithelial Transition Factor (c-MET) Protein Kinase Inhibitors and Identification of the Clinical Candidate 2-(4-(1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the Treatment of Cancer.

Guidelines for the use and interpretation of assays for monitoring autophagy.

Highly ordered nanorod assemblies extending over device scale areas and in controlled multilayers by electrophoretic deposition.

Insights into the aberrant activity of mutant EGFR kinase domain and drug recognition.

Circularized synthetic oligodeoxynucleotides serve as promoterless RNA polymerase III templates for small RNA generation in human cells.

Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1.

Dose-dependent effects of vitamin D on transdifferentiation of skeletal muscle cells to adipose cells.

Atomically abrupt silicon-germanium axial heterostructure nanowires synthesized in a solvent vapor growth system.

Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.

Colloidal synthesis of Cu2SnSe3 tetrapod nanocrystals.

Autophagy in tumour cell death.

Compositionally tunable photoluminescence emission in Cu2ZnSn(S(1-x)Se(x))4 nanocrystals.

Lessons from (S)-6-(1-(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)ethyl)quinoline (PF-04254644), an inhibitor of receptor tyrosine kinase c-Met with high protein kinase selectivity but broad phosphodiesterase family inhibition leading to myocardial degeneration in rats.

Core-shell tin oxide, indium oxide, and indium tin oxide nanoparticles on silicon with tunable dispersion: electrochemical and structural characteristics as a hybrid Li-ion battery anode.

Glucose-starved cells do not engage in prosurvival autophagy.

Colloidal synthesis of homogeneously alloyed CdSe(x)S(1-x) nanorods with compositionally tunable photoluminescence.

Role of autophagy in cancer prevention, development and therapy.

p53 status determines the role of autophagy in pancreatic tumour development.

Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance.

Autophagy chews Fap to promote apoptosis.

Structurally diverse low molecular weight activators of the mammalian pre-mRNA 3' cleavage reaction.

High-performance germanium nanowire-based lithium-ion battery anodes extending over 1000 cycles through in situ formation of a continuous porous network.

Fast left prefrontal rTMS reduces post-gastric bypass surgery pain: findings from a large-scale, double-blind, sham-controlled clinical trial.

New insights into the promoterless transcription of DNA coligo templates by RNA polymerase III.

Complete Colloidal Synthesis of Cu2SnSe3 Nanocrystals with Crystal Phase and Shape Control.