Molecular Pharmacology and Pathology Program,
Department of Pathology & Bosch Institute,
Molecular Pharmacology and Pathology Program, Department of Pathology & Bosch Institute
Darius J. R. Lane has not added Biography.
If you are Darius J. R. Lane and would like to personalize this page please email our Author Liaison for assistance.
VDAC1 is a transplasma membrane NADH-ferricyanide reductase.
The Journal of biological chemistry Feb, 2004 | Pubmed ID: 14573604
Voltage-dependent anion-selective channel 1 (VDAC1)--a mitochondrial protein, rediscovered as a novel enzyme in the plasma membrane.
The international journal of biochemistry & cell biology Feb, 2005 | Pubmed ID: 15474974
A highly sensitive colorimetric microplate ferrocyanide assay applied to ascorbate-stimulated transplasma membrane ferricyanide reduction and mitochondrial succinate oxidation.
Analytical biochemistry Feb, 2008 | Pubmed ID: 17949676
Non-transferrin iron reduction and uptake are regulated by transmembrane ascorbate cycling in K562 cells.
The Journal of biological chemistry May, 2008 | Pubmed ID: 18347019
Ascorbate and plasma membrane electron transport--enzymes vs efflux.
Free radical biology & medicine Sep, 2009 | Pubmed ID: 19501649
Transplasma membrane electron transport comes in two flavors.
BioFactors (Oxford, England) , 2008 | Pubmed ID: 19734120
Frataxin, a molecule of mystery: trading stability for function in its iron-binding site.
The Biochemical journal Mar, 2010 | Pubmed ID: 20141512
Voltage-dependent anion-selective channel (VDAC) in the plasma membrane.
FEBS letters May, 2010 | Pubmed ID: 20184885
A role for Na+/H+ exchangers and intracellular pH in regulating vitamin C-driven electron transport across the plasma membrane.
The Biochemical journal Jun, 2010 | Pubmed ID: 20307259
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2010 | Pubmed ID: 20495089
Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron.
The Biochemical journal Nov, 2010 | Pubmed ID: 20819077
Mitochondrial mayhem: the mitochondrion as a modulator of iron metabolism and its role in disease.
Antioxidants & redox signaling Dec, 2011 | Pubmed ID: 21545274
Nitrogen monoxide (NO) storage and transport by dinitrosyl-dithiol-iron complexes: long-lived NO that is trafficked by interacting proteins.
The Journal of biological chemistry Mar, 2012 | Pubmed ID: 22262835
The glutamate aspartate transporter (GLAST) mediates L-glutamate-stimulated ascorbate-release via swelling-activated anion channels in cultured neonatal rodent astrocytes.
Cell biochemistry and biophysics Mar, 2013 | Pubmed ID: 22886112
Mammalian iron homeostasis in health and disease: uptake, storage, transport, and molecular mechanisms of action.
Antioxidants & redox signaling Jun, 2013 | Pubmed ID: 23199217
N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion.
PloS one , 2013 | Pubmed ID: 23437357
Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism.
Biochimica et biophysica acta Jun, 2013 | Pubmed ID: 23481043
Hepcidin, show some self-control! How the hormone of iron metabolism regulates its own expression.
The Biochemical journal Jun, 2013 | Pubmed ID: 23662810
Biochemistry of cardiomyopathy in the mitochondrial disease Friedreich's ataxia.
The Biochemical journal Aug, 2013 | Pubmed ID: 23849057
Anti-plasmodial activity of aroylhydrazone and thiosemicarbazone iron chelators: effect on erythrocyte membrane integrity, parasite development and the intracellular labile iron pool.
Journal of inorganic biochemistry Dec, 2013 | Pubmed ID: 24028863
Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.
Biochimica et biophysica acta Jan, 2014 | Pubmed ID: 24269900
Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transition.
Biochimica et biophysica acta Jan, 2014 | Pubmed ID: 24472573
The Metastasis Suppressor, N-myc Downstream-regulated Gene 1 (NDRG1), Inhibits Stress-induced Autophagy in Cancer Cells.
The Journal of biological chemistry Apr, 2014 | Pubmed ID: 24532803
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved