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Molecular Pharmacology and Pathology Program,
Department of Pathology & Bosch Institute,
Molecular Pharmacology and Pathology Program, Department of Pathology & Bosch Institute
Darius J. R. Lane has not added Biography.
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VDAC1 is a transplasma membrane NADH-ferricyanide reductase.
The Journal of biological chemistry Feb, 2004 | Pubmed ID: 14573604
Voltage-dependent anion-selective channel 1 (VDAC1)--a mitochondrial protein, rediscovered as a novel enzyme in the plasma membrane.
The international journal of biochemistry & cell biology Feb, 2005 | Pubmed ID: 15474974
A highly sensitive colorimetric microplate ferrocyanide assay applied to ascorbate-stimulated transplasma membrane ferricyanide reduction and mitochondrial succinate oxidation.
Analytical biochemistry Feb, 2008 | Pubmed ID: 17949676
Non-transferrin iron reduction and uptake are regulated by transmembrane ascorbate cycling in K562 cells.
The Journal of biological chemistry May, 2008 | Pubmed ID: 18347019
Ascorbate and plasma membrane electron transport--enzymes vs efflux.
Free radical biology & medicine Sep, 2009 | Pubmed ID: 19501649
Transplasma membrane electron transport comes in two flavors.
BioFactors (Oxford, England) , 2008 | Pubmed ID: 19734120
Frataxin, a molecule of mystery: trading stability for function in its iron-binding site.
The Biochemical journal Mar, 2010 | Pubmed ID: 20141512
Voltage-dependent anion-selective channel (VDAC) in the plasma membrane.
FEBS letters May, 2010 | Pubmed ID: 20184885
A role for Na+/H+ exchangers and intracellular pH in regulating vitamin C-driven electron transport across the plasma membrane.
The Biochemical journal Jun, 2010 | Pubmed ID: 20307259
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2010 | Pubmed ID: 20495089
Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron.
The Biochemical journal Nov, 2010 | Pubmed ID: 20819077
Mitochondrial mayhem: the mitochondrion as a modulator of iron metabolism and its role in disease.
Antioxidants & redox signaling Dec, 2011 | Pubmed ID: 21545274
Nitrogen monoxide (NO) storage and transport by dinitrosyl-dithiol-iron complexes: long-lived NO that is trafficked by interacting proteins.
The Journal of biological chemistry Mar, 2012 | Pubmed ID: 22262835
The glutamate aspartate transporter (GLAST) mediates L-glutamate-stimulated ascorbate-release via swelling-activated anion channels in cultured neonatal rodent astrocytes.
Cell biochemistry and biophysics Mar, 2013 | Pubmed ID: 22886112
Mammalian iron homeostasis in health and disease: uptake, storage, transport, and molecular mechanisms of action.
Antioxidants & redox signaling Jun, 2013 | Pubmed ID: 23199217
N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion.
PloS one , 2013 | Pubmed ID: 23437357
Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism.
Biochimica et biophysica acta Jun, 2013 | Pubmed ID: 23481043
Hepcidin, show some self-control! How the hormone of iron metabolism regulates its own expression.
The Biochemical journal Jun, 2013 | Pubmed ID: 23662810
Biochemistry of cardiomyopathy in the mitochondrial disease Friedreich's ataxia.
The Biochemical journal Aug, 2013 | Pubmed ID: 23849057
Anti-plasmodial activity of aroylhydrazone and thiosemicarbazone iron chelators: effect on erythrocyte membrane integrity, parasite development and the intracellular labile iron pool.
Journal of inorganic biochemistry Dec, 2013 | Pubmed ID: 24028863
Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.
Biochimica et biophysica acta Jan, 2014 | Pubmed ID: 24269900
Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transition.
Biochimica et biophysica acta Jan, 2014 | Pubmed ID: 24472573
The Metastasis Suppressor, N-myc Downstream-regulated Gene 1 (NDRG1), Inhibits Stress-induced Autophagy in Cancer Cells.
The Journal of biological chemistry Apr, 2014 | Pubmed ID: 24532803
University of Sydney
Darius J. R. Lane1,
Alfons Lawen2
1Molecular Pharmacology and Pathology Program, Department of Pathology & Bosch Institute, University of Sydney,
2Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University
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