MRC Centre for Inflammation Research
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Spectroscopic studies of Pyrococcus furiosus superoxide reductase: implications for active-site structures and the catalytic mechanism.
Journal of the American Chemical Society Feb, 2002 | Pubmed ID: 11817955
Heterodisulfide reductase from Methanothermobacter marburgensis contains an active-site [4Fe-4S] cluster that is directly involved in mediating heterodisulfide reduction.
FEBS letters Feb, 2002 | Pubmed ID: 11852093
A hyperthermophilic plant-type [2Fe-2S] ferredoxin from Aquifex aeolicus is stabilized by a disulfide bond.
Biochemistry Mar, 2002 | Pubmed ID: 11863449
Superoxide reductase: fact or fiction?
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Jun, 2002 | Pubmed ID: 12072972
Resonance Raman characterization of the mononuclear iron active-site vibrations and putative electron transport pathways in Pyrococcus furiosus superoxide reductase.
Biochemistry Aug, 2002 | Pubmed ID: 12146949
Nitric oxide binding at the mononuclear active site of reduced Pyrococcus furiosus superoxide reductase.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2003 | Pubmed ID: 12655067
Spectroscopic characterization of the [Fe(His)(4)(Cys)] site in 2Fe-superoxide reductase from Desulfovibrio vulgaris.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Jul, 2003 | Pubmed ID: 12764688
Synthesis and structure-activity relationships of novel arylpiperazines as potent and selective agonists of the melanocortin subtype-4 receptor.
Journal of medicinal chemistry Jan, 2004 | Pubmed ID: 14736255
Spectroscopic investigation of the nickel-containing porphinoid cofactor F(430). Comparison of the free cofactor in the (+)1, (+)2 and (+)3 oxidation states with the cofactor bound to methyl-coenzyme M reductase in the silent, red and ox forms.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry Jul, 2004 | Pubmed ID: 15160314
Substituted 3-imidazo[1,2-a]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino-[6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as highly selective and potent inhibitors of glycogen synthase kinase-3.
Journal of medicinal chemistry Jul, 2004 | Pubmed ID: 15267232
Synthesis and biological evaluation of an orally active ghrelin agonist that stimulates food consumption and adiposity in rats.
Bioorganic & medicinal chemistry letters Dec, 2004 | Pubmed ID: 15501059
Persistence of apoptotic cells without autoimmune disease or inflammation in CD14-/- mice.
The Journal of cell biology Dec, 2004 | Pubmed ID: 15611337
LY503430: pharmacology, pharmacokinetics, and effects in rodent models of Parkinson's disease.
CNS drug reviews , 2005 | Pubmed ID: 15867954
Dipeptides as effective prodrugs of the unnatural amino acid (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740), a selective group II metabotropic glutamate receptor agonist.
Journal of medicinal chemistry Aug, 2005 | Pubmed ID: 16078848
Geometries and electronic structures of cyanide adducts of the non-heme iron active site of superoxide reductases: vibrational and ENDOR studies.
Biochemistry Jan, 2006 | Pubmed ID: 16401073
Spectroscopy and electronic structures of mono- and binuclear high-valent non-heme iron-oxo systems.
Journal of inorganic biochemistry Apr, 2006 | Pubmed ID: 16510189
Local amplification of glucocorticoids by 11 beta-hydroxysteroid dehydrogenase type 1 promotes macrophage phagocytosis of apoptotic leukocytes.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2006 | Pubmed ID: 16751407
Comparing the electronic properties of the low-spin cyano-ferric [Fe(N4)(Cys)] active sites of superoxide reductase and p450cam using ENDOR spectroscopy and DFT calculations.
Journal of the American Chemical Society Dec, 2006 | Pubmed ID: 17177406
Azetidinones as vasopressin V1a antagonists.
Bioorganic & medicinal chemistry Mar, 2007 | Pubmed ID: 17234419
Spectroscopic and electronic structure studies of intermediate X in ribonucleotide reductase R2 and two variants: a description of the FeIV-oxo bond in the FeIII-O-FeIV dimer.
Journal of the American Chemical Society Jul, 2007 | Pubmed ID: 17602477
Catalytic effectiveness, a measure of enzyme proficiency for industrial applications.
Trends in biotechnology Mar, 2009 | Pubmed ID: 19193465
Peroxo-type intermediates in class I ribonucleotide reductase and related binuclear non-heme iron enzymes.
Journal of the American Chemical Society Sep, 2009 | Pubmed ID: 19663382
No evidence of human clonally transmissible anogenital cancer.
International journal of surgical pathology Aug, 2010 | Pubmed ID: 20627958
Microscopic uterine lymphangioleiomyomatosis perivascular epithelioid cell neoplasm: a case report with the earliest manifestation of this enigmatic neoplasm.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists Jan, 2011 | Pubmed ID: 21131829
Conditional ablation of macrophages disrupts ovarian vasculature.
Reproduction (Cambridge, England) Jun, 2011 | Pubmed ID: 21393340
Clinicopathologic characteristics of HER2 FISH-ambiguous breast cancer at a single institution.
The American journal of surgical pathology Jan, 2013 | Pubmed ID: 23108020
Teaching while learning while practicing: reframing faculty development for the patient-centered medical home.
Academic medicine : journal of the Association of American Medical Colleges Sep, 2013 | Pubmed ID: 23887006
MAST2 and NOTCH1 translocations in breast carcinoma and associated pre-invasive lesions.
Human pathology Dec, 2013 | Pubmed ID: 24140425
Epidemiology of concussion in sport: a literature review.
Journal of chiropractic medicine Dec, 2013 | Pubmed ID: 24396326
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